Establishment of NAFLD Cohort and Development of Fibrosis Markers — NAFLD  

Fibrosis of Liver Clinical Trial

Official title: Establishment of Non-alcoholic Fatty Liver Disease Cohort and Development of Markers to Predict Histologic Progression of Liver Fibrosis

Status Recruiting

Clinical Trial Summary

This study is designed for establishment of non-alcoholic fatty liver disease patients cohort to development of markers to predict histologic progression of liver fibrosis.

Clinical Trial Description

• Acoustic radiation force impulse elastography and transient elastography

• Liver tissue (frozen tissue, paraffin block)

• Whole blood, Serum

• Fat amount ratio CT (Visceral adipose tissue, Subcutaneous adipose tissue amount)

• Body composition analyzer (InBody scale):Total fat/muscle mass and appendicular skeletal muscle mass

• Pulmonary function test with post-bronchodilator response and DLCo

• EKG, EchoCG, Heart CT (Coronary calcium score), and Pusle wave velocity (AI index, arterial stiffness)

• Brain MRI or CT

• Upper esophagogastroscopy and colonoscopy

• Berlin score questionnaire and Polysomnography ;

Related Conditions & MeSH terms

• Fibrosis
• Fibrosis of Liver

• NCT number: NCT02206841
• Study type: Observational [Patient Registry]
• Source: Seoul National University Boramae Hospital
• Contact: Won Kim, MD,PhD
• Phone: 8228702233
• Email: drwon1@snu.ac.kr
• Status: Recruiting
• Start date: January 1, 2014
• Completion date: December 31, 2030