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Fibrosis; Heart clinical trials

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NCT ID: NCT05241418 Recruiting - Clinical trials for Congenital Heart Disease

Atrial Late Gadolinium Enhancement in Patients With Repaired Congenital Heart Disease

Start date: March 23, 2022
Phase:
Study type: Observational

In this research study the investigators want to learn more about how well the investigators can visualize scar tissue in the heart by MRI. In patients with congenital heart disease who need a procedure in the electrophysiology laboratory, how the MRI findings match the findings in the electrophysiology laboratory is not known. This study works to answer these questions. Participants will undergo a cardiac MRI as part of the routine clinical care that was ordered by their doctors and additional imaging by cardiac MRI will be performed.

NCT ID: NCT03991910 Recruiting - Clinical trials for Rheumatic Heart Disease

The Effect of Ramipril in Suppressing ST2 Expression in Rheumatic Mitral Stenosis Patients

Start date: June 27, 2019
Phase: Phase 3
Study type: Interventional

Objective propose: to investigate the effect of Ramipril in suppressing ST2 (suppression of tumorigenicity 2) in the cardiac mitral valve in patients with Rheumatic Heart Disease. We hypothesized that we hypothesized that ramipril will improve rheumatic mitral valve fibrosis through the downregulation of ST2.