Fibromyalgia Clinical Trial
Official title:
Duloxetine(Cymbalta) for Fibromyalgia: An Open-Label Pilot Study to Assess Potential Mechanisms for Fibromyalgia in Peripheral Tissue Innervation That Could Predict Therapeutic Responsiveness to Duloxetine
The purpose of this study is to examine the characteristics of the nerves and the small veins
in the skin of people with fibromyalgia. The investigators will then use this information to
identify possible processes in the skin that may help explain why some people feel pain
relief with the study drug (duloxetine) and others do not.
Duloxetine affects certain chemicals in the brain called neurotransmitters. An abnormality in
these chemicals is thought to be related to fibromyalgia. Duloxetine is a selective serotonin
and norepinephrine reuptake inhibitor (SNRI), similar to some drugs used for the treatment of
depression. Duloxetine is approved for sale in the United States by the Food and Drug
Administration (FDA) for the treatment of fibromyalgia.
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