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Fibromyalgia clinical trials

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NCT ID: NCT04435886 Recruiting - Fibromyalgia Clinical Trials

Use of a Probiotic in the Treatment of Fibromyalgia (FIBROPROB)

FIBROPROB
Start date: March 2, 2020
Phase: N/A
Study type: Interventional

This study aims to understand the efficacy of two probiotic interventions as prophylaxes of fibromyalgia symptoms in individuals diagnosed. The primary outcome measure will be the progression and treatment of fibromyalgia, defined as a decrease in the Fibromyalgia Impact Questionnaire (FIQ) score, other otucomes will be the effect on the symptoms of anxiety and depression associated with fibromyalgia, defined as a decrease in the Hospital Anxiety and Depression Scale (HAD) score; perception of pain by scoring on a Visual Analogical Pain Scale (VAS), and differences in the patient's usual medical treatment. Finally adverse effects will be evaluated. The study will have two arms: one arm including a probiotic preparation and a placebo arm.

NCT ID: NCT04415866 Recruiting - Fibromyalgia Clinical Trials

Generalized Hypersensitivity in Patients With Fibromyalgia Syndrome

Start date: August 28, 2020
Phase: N/A
Study type: Interventional

Fibromyalgia (FM) is a chronic musculoskeletal pain disorder with unknown causes. Our previous studies showed abnormal sensations of second pain (wind-up), indicating central hypersensitivity as an important mechanism of FM. Triggering events have been implicated as the cause of central hypersensitivity.

NCT ID: NCT04286880 Recruiting - Clinical trials for Myofascial Pain Syndrome

Comparative Efficacy of PRP and Dry Needling in Management of Trigger Points in Masseter Muscle in MPS Patients

Start date: February 24, 2020
Phase: Phase 3
Study type: Interventional

Title: Comparative Efficacy of Platelet Rich Plasma injection and Dry Needling in management of trigger points in masseter muscle in Myofascial Pain Syndrome patients. Rationale: Pain and trismus caused by Myofascial pain syndrome in masticatory muscles are one of the prime concerns for the patients. In the recent times, Platelet Rich Plasma therapy has been studied extensively and has produced promising results. It is used to promote sarcomere repair by concentrating growth factors and decrease inflammation by inhibiting pro-inflammatory and apoptotic cells. Thus, the present study is designed to evaluate the efficacy of Platelet Rich Plasma injection in trigger points in masseter muscle in myofascial pain syndrome patients. Research Question P: Population (Patients with trigger points in masseter muscle) I: Intervention (PRP injection) C: Control (Dry needling) O: Outcome (Improvement in symptom of pain ) T: Time Frame (1 year) S: Study Design (Randomized clinical trial) Setting in Haryana , India Is Platelet Rich Plasma more effective as compared to dry needling alone in treatment of trigger points in masseter muscle in Myofascial Pain Syndrome patients ?

NCT ID: NCT04274036 Recruiting - Fibromyalgia Clinical Trials

Evaluation of Stigma and Related Factors in Fibromyalgia

Start date: February 13, 2020
Phase:
Study type: Observational

Stigmatization is especially studied in mental disorders such as schizophrenia. In recent years, different chronic diseases such as AIDS, tuberculosis, and diabetes have also been shown to decrease in quality of life due to the "stigma" of these patients.

NCT ID: NCT04248478 Recruiting - Fibromyalgia Clinical Trials

Eating Behaviours in Female Patients With Fibromyalgia

Start date: January 29, 2020
Phase:
Study type: Observational

The Relationship Between Eating Behaviours and Health Status of Female Patients with Fibromyalgia

NCT ID: NCT04220567 Recruiting - Fibromyalgia Clinical Trials

Effectiveness of Exercise and Patient-centred Education on Fibromyalgia

Start date: January 7, 2020
Phase: N/A
Study type: Interventional

This study aims to compare the effects of an eight-week exercise and patient-centred education programme with eight-week exercise alone programme on disability, pain intensity, health-related quality of life and patient global impression of change. A prospective, parallel, double-blinded and multi-centre randomised controlled trial will be carried out.

NCT ID: NCT04206397 Recruiting - Fibromyalgia Clinical Trials

Mechanisms of Affective Touch in Chronic Pain

MATCP
Start date: September 15, 2021
Phase: N/A
Study type: Interventional

This study compares how different types of touch found in massage therapies impact pain perception, and whether these effects differ in individuals with and without chronic pain. This study also examines psychological factors that may predict differences in touch perception in individuals with chronic pain. This research will improve our understanding of whether and how massage therapies can benefit pain and health, and whether this differs in people who suffer from chronic pain.

NCT ID: NCT04192058 Recruiting - Fibromyalgia Clinical Trials

Effect of Transcranial Direct-current Stimulation in Eating Behavior of Women With Fibromyalgia

Start date: September 15, 2019
Phase: N/A
Study type: Interventional

Introduction: Fibromyalgia (FM) is a syndrome characterized by generalized musculoskeletal pain, fatigue, non-repairing sleep, cognitive changes, depressive symptoms and other correlates of autonomic dysfunction. A high prevalence of overweight in patients with fibromyalgia is observed, about 80% according to current data, which affects the course and prognosis of the disease, besides overburdening health costs and further compromising quality of life. life of these patients. Evidence shows possible pathophysiological pathways shared by these two pathologies, as well as aspects related to food behavior. It is known that dopaminergic neurotransmission is altered in both, suggesting an increase in the sensitivity or density of D2 dopamine receptors. Non-pharmacological options for pain management and dysfunctional eating behavior include the important contribution of neuromodulatory techniques of non-invasive cerebral stimulation, such as transcranial direct current stimulation (tDCS), which aims to increase resisting hyperpalatable foods and reducing caloric intake. Objectives: To evaluate the association between dopamine receptor-2 (DRD2) Taq1A allele A1 polymorphism (rs1800497) and to observe the possible effect of tDCS on the dorsolateral prefrontal cortex (DLPFC) on homeostatic and hedonistic aspects of eating behavior in women with FM. Methods: A randomized, double blind, parallel group, controlled trial with simulated treatment will be performed. Will be included in the study women literate, right-handed, with confirmed diagnosis of FM. The evaluation will be done through questionnaires on pain and eating behavior, anthropometric evaluation and biochemical measurements. The intervention will take place through active or simulated home for 4 weeks. Perspectives: To evaluate dysfunctional neuroplastic changes in eating behavior and biological markers and also to serve as a basis for future effective treatment strategies through neuromodulation and nutritional counseling.

NCT ID: NCT04128813 Recruiting - Fibromyalgia Clinical Trials

A Comparison of the Effect of Two Types of Whole Body Vibration on Fibromyalgia. A Randomized Controlled Trial.

Start date: October 16, 2019
Phase: N/A
Study type: Interventional

The objective of this study is to compare the effectiveness of two types of body vibration platform, one vertical and one rotational, through a 12-week training in patients with fibromyalgia.

NCT ID: NCT04107948 Recruiting - Physical Activity Clinical Trials

Efficiency of an Optimized Care Organization for Fibromyalgia Patients. The FIMOUV 2 Study

FIMOUV 2
Start date: January 23, 2020
Phase: N/A
Study type: Interventional

Fibromyalgia affects 2 to 5% of adults in the general population. Patients describe a combination of symptoms centred around fatigue not induced by exercise and not relieved by rest. The diagnosis of fibromyalgia is self-perpetuating by the deconditioning, consequence of a reduced muscle mass due to inactivity and periods of prolonged rest. Thus, it seems fundamental to develop other non-drug approaches: among them, adapted physical activity is recommended by most learned societies because of a good level of evidence (Level 1, Grade A). The question remains, however, whether simple advice to resume physical activity is sufficient (routine care with medical assessment at 3 months) or whether a physical activity supervised inside and outside the hospital is not more relevant.