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Clinical Trial Summary

The study team will be randomizing patients presenting for open myomectomy to either received transversus abdominal plane blocks with either liposomal bupivacaine or standard bupivacaine. The study team will be analyzing the impact of local anesthetic on opiate consumption as the investigator's primary endpoint with other secondary endpoints.


Clinical Trial Description

After consent, patients will be randomized to either liposomal bupivacaine Transversus Abdominal Plane (TAP) vs standard bupivacaine TAP. Blocks will occur post induction and pre incision. Only the block team (not the anesthesia team nor the care team) will be unblinded and they will not have any impact on the data collection. The entire care team and the patient will be blinded. A standardized anesthetic regimen will be employed followed by a prescriptive post-operative pain management plan aimed at enhanced recovery. Patients will be followed for up to 96 hours and asked about their opiate consumption, pain scores, side effects, and recovery. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04272086
Study type Interventional
Source Icahn School of Medicine at Mount Sinai
Contact Daniel Katz, MD
Phone 212-241-7475
Email daniel.katz@mountsinai.org
Status Recruiting
Phase Phase 4
Start date November 9, 2020
Completion date August 2024

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