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Fibrinogen clinical trials

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NCT ID: NCT05391412 Recruiting - Bleeding Clinical Trials

Effect of Prophylactic Fibrinogen Concentrate In Scoliosis Surgery

EFISS
Start date: June 6, 2022
Phase: Phase 4
Study type: Interventional

EFISS is a prospective, randomized, placebo-controlled trial testing the feasibility, safety and efficacy of prophylactic administration of fibrinogen in paediatric spinal surgery. The study is monocentric and will be conducted in University Hospital Brno, Czech Republic. This is a pilot study in which the primary objective will be to evaluate the feasibility of a clinical trial in 32 selected patients undergoing scoliosis surgery. Participants will be randomized into study groups in a 1:1 allocation ratio and followed up for 28 days after surgery. The expected duration of this clinical trial is 8 months.

NCT ID: NCT05272072 Completed - Hip Fractures Clinical Trials

Evaluation of Relationship Between Preoperative Fibrinogen/Albumin Ratio and Morbidity After Hip Fracture Operations

Start date: March 30, 2022
Phase:
Study type: Observational [Patient Registry]

Due to the aging of populations, hip fracture operations are increasing from year to year. This operations have many complications also high morbidity and the mortality. Population of this study is oldest old age patients who will have an operation because of hip fracture. The primary outcome of this study is evaluation of relationship between preoperative fibrinogen/albumin ratio and the morbidity after hip fracture operations. The secondary outcomes of this study is evaluation of relationships between fibrinogen/albumin ratio and mortality, length of stay in ICU, length of stay in hospital, postoperative complications, blood product consumption. The study will be completed after the records of preoperative, intraoperative data and the data of the first 30 days postoperatively in this population.

NCT ID: NCT03075774 Not yet recruiting - Cardiac Surgery Clinical Trials

Observational Study About the Use of Fibrinogen in Adult Cardiac Surgery

Start date: March 2017
Phase: N/A
Study type: Observational [Patient Registry]

Multicenter prospective observational study, involving all adult patients who underwent cardiac surgery with extracorporeal circulation

NCT ID: NCT01187225 Completed - Clinical trials for Cardiac Surgical Procedures

Fibrinogen Concentrate In Children After Cardiac Surgery

FiCCS
Start date: August 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate prospectively whether concentrate fibrinogen reduces blood losses, transfusion requirements and occurrence of clinical complications compared to cryoprecipitate in children after cardiac surgery with pump.