Fetal Ovarian Cyst Clinical Trial
Official title:
Pubertal Evolutionary Profile of Children Monitored for Fetal Ovarian Cyst
This study is based on pubertal surveillance of fetal ovarian cysts (KOF). Fetal ovarian cysts (KOF) detected during fetal ultrasound examinations occur during the 3rd trimester of pregnancy and are of unknown cause.
These cysts are functional in the vast majority of cases and are therefore likely to
disappear spontaneously, but they may become complicated before regressing. Apart from
complication, the natural evolution of these cysts, which are said to be "simple" because
they are liquid on ultrasound, is towards regression in the first months of neo-natal life.
Surveillance during the 1st year of life showed that simple cysts regressed during the 1st
trimester. In the case of complicated cysts, oophorectomy was necessary in 9 cases. In the
1-year follow-up, the ovarian recovery rate was significantly different depending on the
appearance of the cyst (p<0.0001); 60 ovaries out of 89 homolateral to the cyst were
follicular, of which 48/49 (98%) were carriers of fluid cysts and 12/40 (30%) were initially
heterogeneous. The origin of these cysts is unknown, the ovary is again physiologically
stimulated during the onset of puberty. No series in the literature gives the long-term
ovarian prognosis for these patients. We wish to evaluate the pubertal evolutionary profile
of patients followed at the University Hospital for KOF. The data collected concerning
puberty (age of menses) will be examined in relation to the age of menses in the siblings and
in the mother, as well as to the data in the literature on the age of the first menses in
France.
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