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Polar Body Removal Before ICSI for Oocyte Activation in Previous Fertilization Failure Cases — PBRBICSI  

Fertilization Clinical Trial

Official title:
Polar Body Removal Before ICSI as a Method of Oocyte Activation in Previous Fertilization Failure Cases

Clinical Trial Summary

Cases which undergone ICSI before with failure of fertilization will do another ICSI cycle with removal of the polar body just before the ICSI procedure and sperm injection at the site of polar body removal. This study group will be evaluated with another group with the classic ICSI procedure

Clinical Trial Description

Patients with previous fertilization failure will be divided into 2 groups:

Group 1 (control): Will undergo classic ICSI procedure in half the MII oocyte of the same case.

Group 2 (study group): The other half of the MII oocyte of the same case will undergo:

1. Polar body removal.

2. ICSI procedure with injection of the spermatozoon in the same zona opening (done by laser for polar body removal).

Results: Will be collected with evaluation of number of 2PN zygotes, Day 1, Day 2, Day 3, Day 5 embryos in all the cases. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02913781
Study type Interventional
Source Benha University
Contact
Status Completed
Phase N/A
Start date February 2016
Completion date January 2018
View Details
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