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Clinical Trial Details — Status: Active, not recruiting

Administrative data

NCT number NCT00827476
Other study ID # 0530-08-HMO- CTIL
Secondary ID
Status Active, not recruiting
Phase Phase 0
First received January 21, 2009
Last updated January 21, 2009
Start date January 2009
Est. completion date January 2015

Study information

Verified date January 2009
Source Hadassah Medical Organization
Contact n/a
Is FDA regulated No
Health authority Israel: Ministry of Health
Study type Interventional

Clinical Trial Summary

we will perform xenotransplantation and in vitro culture of ovarian tissue from patients undergoing ovarian cortex cryopreservation.


Description:

Ovarian tissue is removed by laparoscopy and only in patients facing premature ovarian failure due to chemotherapy.Tissue for research will consist either of a small portion (<10%) of the cortex for preservation for young women. another source of ovarian tissue for research will be obtained following consent from family of patients who have died of the disease and have previously frozen ovarian tissue.


Recruitment information / eligibility

Status Active, not recruiting
Enrollment 100
Est. completion date January 2015
Est. primary completion date January 2012
Accepts healthy volunteers No
Gender Female
Age group 5 Years to 40 Years
Eligibility Inclusion Criteria:

- tissue previously obtained

Exclusion Criteria:

- no tissue available or no consent

Study Design

Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment


Related Conditions & MeSH terms


Intervention

Procedure:
ovarian transplantation
ovarian xenotransplantation or in vitro culture

Locations

Country Name City State
n/a

Sponsors (2)

Lead Sponsor Collaborator
Hadassah Medical Organization Israel Science Foundation

Outcome

Type Measure Description Time frame Safety issue
Primary improving folliculogenesis and oocuyte maturation after ovarian transplantation 2 years No
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