Premature Birth Clinical Trial
Official title:
A Clinical Multi-Center Study of Efficacy Analysis in Different Doses of Domperidone in Feeding Intolerance of Premature Infant
The purpose of this clinical multi-center study is to determine whether different doses of domperidone are effective in the treatment of feeding intolerance in premature infant
the premature infant have been divided into four group.The first group take the 0.2mg/kg/tds
domperidone as treatment ,while the other group take the 0.4mg/kg/tds
domperidone,0.6mg/kg/tds domperidone and the placebo respectively .
An objective index has been decided to evaluate the severity of feeding intolerance in the
premature infant. 3kg/kg 5% glucose will be injected into the gastric tube .The residual
glucose will be drawed out from the gastric tube. The residual percentage is the main result
of the study.
The main result will be compared by the secondary result to help to explain the accuracy. The
secondary result is the percentage of residual milk drawed out from the gastric tube from how
many milk the infant take 3 hours ago.
Any adverse effect will be recorded and analysed to figure out whether is associate with the
domperidone.
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