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Feeding Disorder Neonatal clinical trials

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NCT ID: NCT03743207 Completed - Prematurity Clinical Trials

Preterm Infants May Better Tolerate Warmer Feeds

Prematurity
Start date: October 1, 2012
Phase: N/A
Study type: Interventional

Feeding intolerance is frequent among preterm infants in neonatal intensive care units (NICUs). Although there are many studies about enteral nutrition strategies and content in preterm infants, no evidence-based standards exist for the optimal milk temperature for preterm infants. Therefore, in this study the investigators aimed to examine the effects of feeding temperature and the possible morbidities.

NCT ID: NCT03552510 Completed - Preterm Infant Clinical Trials

Oropharyngeal Administration of Mother's Milk in Preterm Infants and Gastrointestinal Motility

OPAMM
Start date: June 1, 2016
Phase: N/A
Study type: Interventional

Mother's milk does not come in contact with the oropharyngeal pouch of preterm infants during gavage feeding. We hypothesized that stimulation of the oropharyngeal pouch using small amount of the mother's milk 5 minutes before initiation of regular gavage feeding will increase the level of GIT hormones.

NCT ID: NCT03498989 Not yet recruiting - Weight Gain Clinical Trials

Effect of Early Feeding of Breast Milk

Start date: June 21, 2018
Phase: N/A
Study type: Interventional

Breast milk is an extremely complex and highly variable biofliud that has evolved to nourish infants and protect them from disease whilst their own immune system matures. The composition of human breast milk changes in response to many factors, matching the infants requirement according to its age and other characteristics.

NCT ID: NCT02971566 Completed - Clinical trials for Placental Insufficiency

Splanchnic Oxygenation Response to Enteral Feeds in Preterm Infants With Abnormal Antenatal Doppler.

AREDF-SO
Start date: February 2013
Phase: N/A
Study type: Observational

Antenatal absent or reversed end-diastolic flow (AREDF) velocity through the umbilical arteries places preterm infants at significant risk for developing gastrointestinal complications, such as feeding intolerance, necrotizing enterocolitis or spontaneous intestinal perforation. Due to the fear of the aforementioned conditions, the establishment of adequate enteral feeds is frequently hampered in this population. Previous postnatal Doppler studies have shown that AREDF preterm infants who later developed feeding intolerance have a decreased blood flow velocity in the superior mesenteric artery in response to the first enteral feed; to date, however, it is not known whether this hemodynamic impairment persists over time, or if it is associated with reduced splanchnic oxygenation and perfusion, monitored by Near-infrared spectroscopy (NIRS). This observational prospective study aims: - to assess the patterns of abdominal oxygenation and perfusion in response to enteral feeds in AREDF preterm infants at different phases of enteral feeding establishment; - to evaluate a possible correlation with the development of gastrointestinal complications.

NCT ID: NCT01236833 Active, not recruiting - Intestinal Disease Clinical Trials

Lactated Ringer's Solution in Neonates With Feeding Intolerance

LR
Start date: November 2010
Phase: Phase 2
Study type: Interventional

The objective of this study is determining if enteral administration of Lactated Ringer's solution (LR) in preterm infants with feeding intolerance enables for faster advancement of milk feeding than fasting.