mNGS Versus Blood Culture in FN

Status Recruiting

Clinical Trial Summary

Blood stream infection (BSI) during febrile neutropenia (FN) is a lethal complication, while confirmed diagnosis via blood culture is usually with low sensitivity and time delay. The new technique of metagenome next generation sequencing (mNGS) has the potential of early and more accurate detection of pathogens. However, this technique has not been well validated for BSI diagnosis in patients with hematological disease. Therefore, we designed a prospective multicenter study to compare the diagnosis performance in BSI.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05149547
Study type	Observational
Source	Peking University People's Hospital
Contact	Yuqian Sun, MD
Phone	861088324577
Email	sunyuqian83@hotmail.com
Status	Recruiting
Phase
Start date	October 15, 2021
Completion date	August 31, 2022

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT06055777` - Study of the Safety, Tolerability, and PK of SZEY-2108 Administered Intravenously to HVs in SAD and MAD Cohorts	Phase 1
Recruiting	`NCT05793983` - S100A8/A9 and Innate Immunity in Liver Disease
Active, not recruiting	`NCT05963269` - The Effect of the Game on Students' Intramuscular Injection Skills	N/A
Not yet recruiting	`NCT02222779` - Quantification of Transition Metals	N/A
Completed	`NCT01976234` - Stored RBC Transfusion and Immonomodulation	N/A
Completed	`NCT02345135` - Susceptibility to Infections in Ataxia Telangiectasia	N/A
Completed	`NCT01530763` - Safety and Efficacy Study of Ceftaroline Versus a Comparator in Pediatric Subjects With Community Acquired Bacterial Pneumonia (CABP)	Phase 2/Phase 3
Completed	`NCT01158560` - A Trial of Vitamin D and Health Advice for the Prevention of Upper Respiratory Tract Infections	Phase 3
Completed	`NCT01176786` - Reusable Versus Disposable Draping System in Breast Reconstruction Surgery	N/A
Active, not recruiting	`NCT05284097` - Ad26.ZEBOV, MVA-BN-Filo Vaccination in Children and Adults Previously Vaccinated With Control in the EBOVAC-Salone Study	Phase 2
Enrolling by invitation	`NCT06055712` - Antibiotic Prophylaxis in Pediatric Open Fractures	Phase 4
Not yet recruiting	`NCT06338345` - Pharmacokinetics and Modelling of Beta-Lactam in ECMO-VA Patients	N/A
Recruiting	`NCT06002685` - Partners in Children's Health (CSN): A Randomized Trial of an Attachment Based Intervention	N/A
Completed	`NCT02802059` - E. Coli Nissle 1917 - Suspension for Infection Prophylaxis	Phase 3
Completed	`NCT05289674` - The Effect of Lactoferrin in High Calorie Formula on IL-6 and IL10 in Children With Failure to Thrive and Infection	N/A
Recruiting	`NCT05770765` - Creation of a Bank of Biological Materials and Associated Data Related to Patients With Infectious and Tropical Diseases
Completed	`NCT05389540` - Rural South and Southeast Asia Household Health Survey
Completed	`NCT05080920` - Rosmalip® for Cancer Infections Prevention	N/A
Recruiting	`NCT05287438` - Next Generation Sequencing Versus Traditional Cultures for Clinically Infected Penile Implants: Impact of Culture Identification on Outcomes	N/A
Recruiting	`NCT05610098` - Gene Expression Profiles in Spinal Tuberculosis.