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Febrile Neutropenia clinical trials

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NCT ID: NCT01268878 Completed - Clinical trials for Squamous Cell Head and Neck Carcinoma

Hematologic Toxicity Observation of the Docetaxel+ Cisplatin+ Fluorouracil (TPF)Medical Protocol

OTOHTPF
Start date: June 2010
Phase: N/A
Study type: Observational

The ending of this study is to describe the effect of febrile neutropenia on patients who receive a chemotherapy by docetaxel+cisplatin+fluorouracil(TPF).

NCT ID: NCT01216241 Terminated - Febrile Neutropenia Clinical Trials

Daptomycin Versus Placebo in Patients With Neutropenia and Fever

Start date: April 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the benefits and side effects of daptomycin compared to placebo for the treatment of neutropenic fever.

NCT ID: NCT01144793 Completed - Leukemia, Myeloid Clinical Trials

Biomarker To Evaluate Protein Profiles of Neutropenic Fever/Infection With Acute or Chronic Leukemias

Start date: April 2008
Phase: N/A
Study type: Observational

The purpose of this study is to measure, in pilot/observational study, panels of circulating proteins in real time at the onset of neutropenic fever/infection in patients with acute or chronic leukemias undergoing chemotherapy or other biologic treatment. And to generate preliminary trend results in panels of circulating proteins longitudinally during the period of neutropenia and to correlate those values to clinical/laboratory data and patient outcomes.

NCT ID: NCT01114165 Completed - Sepsis Clinical Trials

Value of the LightCycler® SeptiFast Test MGRADE for the Pathogen Detection in Neutropenic Hematological Patients

Start date: May 2010
Phase: Phase 4
Study type: Interventional

The overall objective of this study is to assess the clinical value of the SeptiFast Test as an adjunct to traditional microbiological, clinical, and other laboratory assessments in early detection and identification of a potential pathogen and therefore early targeted antimicrobial management of neutropenic hematological patients with suspected infection or sepsis.

NCT ID: NCT01034059 Completed - Neutropenic Fever Clinical Trials

Assessment of sTREM-1 as a Diagnostic Marker in Patients With Neutropenic Fever

Start date: October 2008
Phase: N/A
Study type: Observational

The soluble triggering receptor expressed on myeloid cells-1 (sTREM-1) was an established biomarker useful for infection in non-neutropenic patients. In this study, we tested sTREM-1 in the patients with neutropenic fever. Pro-calcitonin (PCT) and C-reactive protein (CRP) were also measured. We planned to investigate and explore the role of sTREM-1 in early diagnosis of infection in patients with neutropenic fever.

NCT ID: NCT00945555 Completed - Febrile Neutropenia Clinical Trials

Observational Non-Interventional Study Of Febrile Neutropenia Patients To Evaluate Antibacterial Therapeutical Options

Start date: June 2009
Phase: Phase 4
Study type: Observational

The purpose of this study was to define and classify antibacterial agents used in Turkey for patients with febrile neutropenia.

NCT ID: NCT00928291 Completed - Febrile Neutropenia Clinical Trials

Procalcitonin Protocol to Shorten the Antibiotic Therapy in Febrile Neutropenia

Start date: January 2010
Phase: N/A
Study type: Interventional

In this study the investigators aim to test if a procalcitonin (PCT) - guided strategy allows to reduce the antibiotic use in patients with febrile neutropenia hospitalized in a Brazilian tertiary university hospital, causing no harm.

NCT ID: NCT00913042 Completed - Neutropenia Clinical Trials

Assessment of New Blood Culture Methods on the Microbiological Documentation of Febrile Neutropenia

HEMATOCPLUS
Start date: February 2008
Phase: N/A
Study type: Observational

Febrile neutropenia are microbiologically documented in only 30% of the cases, and almost exclusively by blood cultures. The reasons for this low documentation are likely multiple: (1) some of these fevers are of non-infectious origin. (2) The bacterial inoculum present in the blood may be low and consequently undetectable by conventional blood cultures. The primary objective of the study is to assess new blood culture procedures and technics, in order to improve the diagnostic yield of blood cultures during febrile neutropenic episodes.

NCT ID: NCT00784368 Completed - Neutropenia Clinical Trials

A Pharmacokinetic Study of JK1211(Itraconazole [Itrizole]) Oral Solution in Participants With Deep Mycosis and Those With Febrile Neutropenia Suspected of Fungal Infection

Start date: January 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the pharmacokinetics (how the drug is absorbed in the body, distributed within the body, and how it is removed from the body over time) of itraconazole (ITCZ) oral solution in participants with Systemic Fungal Infection (SFI) and those with febrile (with fever) neutropenia (FN, decrease in white blood cells) suspected of fungal infection.

NCT ID: NCT00781040 Completed - Sepsis Clinical Trials

Neutropenic Fever, Inflammatory Markers and Sepsis in Haematological Patients

Start date: December 2006
Phase:
Study type: Observational

The aim of this study is to find out whether inflammation markers including cardiac markers have predictive value in evaluation of pathogenesis of sepsis in neutropenic haematological patients.