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Feasibility clinical trials

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NCT ID: NCT04781998 Completed - Clinical trials for Overweight and Obesity

Is Saxenda® a Viable Treatment of Obese Patients in Forensic Psychiatry?

Start date: July 1, 2021
Phase: Phase 4
Study type: Interventional

An open-label, multi-centre, 26-weeks clinical feasibility study. The objective is to explore whether Saxenda could be a feasible choice in the treatment of overweight, obesity and weight-related medical problems, in patients diagnosed with a severe mental illness and hospitalized at a forensic department in Denmark. We wish to determine the viability of the daily Saxenda®-injection treatment in this specific patient group.

NCT ID: NCT04553159 Completed - Safety Clinical Trials

Autologous Adipose Derived Stem Cells Transplantation in the Treatment of Keloids.

Start date: March 1, 2021
Phase: Phase 2
Study type: Interventional

Keloids are the most common disfiguring skin disorder affecting colored population with a prevalence of upto 16%. Autologous adipose derived stem cells have been found to have potential therapeutic benefits however limited clinical trials have compared there role to standard therapy. This is a pilot study that is intended to evaluate the feasibility of conducting this clinical trial comparing adipose derived stromal vascular fraction to Triamcinolone in keloid treatment. The full clinical trial is already registered under the clinical trial number NCT04391621. The objective of this Pilot is to evaluate the feasibility of conducting a full study on the same topic.

NCT ID: NCT04505345 Active, not recruiting - Cognitive Function Clinical Trials

Virtual Reality Cognitive Training in Alcohol Use Disorder

Start date: September 30, 2017
Phase: N/A
Study type: Interventional

This study aims to test the feasibility of using exercises in virtual reality for cognitive training of patients with alcohol use disorder undergoing residential treatment.

NCT ID: NCT04486677 Completed - Feasibility Clinical Trials

Caring Cards to and From Veterans: A Peer Approach to Suicide Prevention

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Veteran suicide is a national problem; social disconnection is an important contributor to suicide risk. This pilot study will recruit Veterans to take part in a peer-centered intervention called Caring Cards (CC). CC gives Veterans who have a history of increased suicide risk the opportunity to make cards that are then sent to Veterans who are currently at high-risk for suicide. This study will directly benefit Veterans and contribute to the quality of services provided by VA by creating a safe, creative space for Veterans with lived experience related to suicide risk to join together to provide messages of hope, community, and resilience to their peers at risk for suicide. Helping Veterans support one another provides a bridge for social connection, which may help prevent Veteran suicide. This intervention may also improve Veterans' satisfaction with VA healthcare and engagement with mental health treatment.

NCT ID: NCT04305990 Not yet recruiting - Feasibility Clinical Trials

Demand-Driven Method for Gas Delivery in a Dental Setting

Start date: March 2020
Phase: N/A
Study type: Interventional

This study compares two methods of gas delivery in a dental setting: 1) demand-driven (DD) and 2) free-flow (FF). Nitrous oxide and oxygen sedation (NOS) is a common form of minimal sedation for adult and paediatric patients undergoing dental procedures. In order for NOS devices to be utilized during dental treatment, dentists must be able to provide gas flow to the patient, and subsequently scavenge used and unused gasses. Gas delivery is via a nasal mask, since the oral cavity must be accessible to the dentist throughout treatment. Current devices for NOS in the dental setting utilize a free-flow gas method, where nitrous oxide and oxygen are released continuously from their tanks. The flow rate is set by the dentist according to the patient's minute ventilation needs, and unused and exhaled gasses are scavenged via the nasal mask. The demand-driven gas flow method, where inspiration triggers gas flow, has been used successfully in other medical settings, such as in obstetrics, medical emergencies, and for patients with chronic obstructive pulmonary disease. However, in these settings the mask used covers both the nose and mouth, and patients can trigger the demand-driven method through inspiration of the nose or mouth. The demand-driven gas flow method has a significant gas-sparing advantage over the free-flow method. With a demand-driven method, the patient dictates the flow rate and gas is only delivered when they are inspiring, compared to the free-flow method which provide gas flow throughout inspiration and expiration. However, the demand-driven method have not been studied in a dental setting where flow can only be triggered through the nose. It is therefore unknown whether it is feasible or comfortable for patients to trigger a demand-driven method nasally when their mouth is open during dental treatment. This study will aim to assess the feasibility and comfort of a nasal demand-driven gas delivery method utilizing 100% oxygen in healthy, adult participants in a simulated dental setting. If the device is feasible and comfortable with 100% oxygen in a simulated dental setting, future research can be conducted to assess its use for NOS for dental treatment.

NCT ID: NCT04169724 Completed - Feasibility Clinical Trials

Meditation for Burnout in PA Students

Start date: September 30, 2019
Phase: N/A
Study type: Interventional

This study investigates the feasibility and effects of an app-based mindfulness meditation intervention for PA students.

NCT ID: NCT04150354 Completed - Mental Health Issue Clinical Trials

Mental Health Symptom Monitoring Utilizing the Cogito Behavioral Analytic Platform

Start date: October 28, 2016
Phase: N/A
Study type: Interventional

The primary objective of this project is to test the acceptability and feasibility of a mobile application to facilitate mental health symptom monitoring and follow-up among Veterans. During the course of the study, the research application will be installed on participants' mobile phone. The application on the participants' phone will be recording data about their behavior. Participants will also be asked to complete bi-weekly surveys via the app.

NCT ID: NCT03806465 Active, not recruiting - Safety Clinical Trials

Malaria Vaccine Pilot Evaluation

MVPE
Start date: February 25, 2019
Phase:
Study type: Observational

The RTS,S/AS01 malaria vaccine is being introduced sub-nationally in phased pilot introductions through the EPI programmes in Malawi Ghana and Kenya. Vaccine introduction is by the respective MoH in selected areas randomly assigned to receive the vaccine at the beginning of the pilots. In the context of this programmatic activity, the Malaria Vaccine Pilot Evaluation (MVPE) registered here as observational evaluations during early vaccine introduction, include a series of 3 household surveys, and sentinel hospital and community mortality surveillance, building on routine systems. These observational evaluations will measure: 1. The programmatic feasibility of delivering a 4 dose schedule; 2. Safety in routine use, with focus on cerebral malaria and meningitis; 3. The impact of the malaria vaccine in routine use on severe malaria and all-cause mortality

NCT ID: NCT03766165 Completed - Feasibility Clinical Trials

Microenterprise Intervention to Reduce Sexual Risk Behaviors in Young Adults

EMERGE
Start date: December 5, 2018
Phase: N/A
Study type: Interventional

The study team will conduct a two-group study to examine the feasibility of implementing an enhanced microenterprise intervention to reduce sexual risk behaviors. The team will enroll approximately 40 young adults. Participants will be randomly assigned to one of two groups. The first group ("control") will receive text messages with information on job openings. The second group ("intervention") will receive text messages with information on job openings plus HIV prevention and business educational sessions, mentored apprenticeship, a start-up grant (provided in 6 payments), and HIV behavioral economics text messages.

NCT ID: NCT03713151 Completed - Exercise Clinical Trials

Feasibility of a Blended Therapy Approach

bletheRD
Start date: February 27, 2019
Phase: N/A
Study type: Interventional

Exercise is an important part of therapy guidelines in the rehabilitation of rare diseases (RDs) as Haemophilia and Myositis. The aim of this study is not to evaluate a new therapy intervention, but to evaluate the delivery of this intervention. In clinical practice, patients are usually instructed to perform an exercise program at home. Normally, a physiotherapist (PT) provides an instruction (paper-) sheet. In this study, the investigators evaluate the feasibility of an interactive tablet-based way of delivery. The exercise program is - as usual in physiotherapy - individually tailored by the PT.