Quantification of Hepatic Steatosis With Different Ultrasound Frequency

Status Active, not recruiting

Clinical Trial Summary

The objective of this study is: (1) to compare the feasibility (technical successes rate and reliability) in measuring attenuation coefficient between two different frequencies (3MHz, 4MHz) of ultrasound beam; (2) to evaluate and compare the diagnostic performance of attenuation coefficient for steatosis using two different frequencies (3MHz, 4MHz) of ultrasound beam by comparison with the pathologic results acquired by liver biopsy or surgery.

Clinical Trial Description

Investigators measure the distance between the skin and liver capsule on B-mod images. Investigators place a region of interest (ROI) avoiding reverberation artifacts and acquire attenuation coefficient for five times. For participants who require a liver biopsy, investigators try to target the same area in the liver, where ROI was placed. Investigators evaluate hepatic steatosis, lobular inflammation, and fibrosis of tissue of the liver using a scoring system suggested by Nonalcoholic Steatohepatitis Clinical Research Network. ;

Study Design

Related Conditions & MeSH terms

Fatty Liver
Fatty Liver, Nonalcoholic
Non-alcoholic Fatty Liver Disease
Ultrasound

Clinical Trial Details

NCT number	NCT05855239
Study type	Observational [Patient Registry]
Source	Asan Medical Center
Contact
Status	Active, not recruiting
Phase
Start date	June 8, 2023
Completion date	December 31, 2024

View Details

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