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Effects of Dietary Manipulation on Metabolism in Healthy Adults

Fasting Clinical Trial

Official title:
Effects of Dietary Manipulation on Metabolism in Healthy Adults

Clinical Trial Summary

This study will examine the potential changes in the blood levels of a recently discovered metabolic regulator in response to changes in diet in healthy adults. Our hypothesis is that in healthy adults key regulatory factors involved in lipid oxidation will respond to changes in diet, particularly fasting and diet-induced ketosis.

Clinical Trial Description

There is scant data regarding the metabolic events that occur in humans during ketosis which may be brought about by fasting or ingestion of diets low in carbohydrate. We aim to employ both fasting and dietary manipulation in order to bring about a ketotic state in healthy human adults. During the study blood levels of key metabolic regulators will be monitored 1) during a 16 hour fast followed by re-feeding and 2) during dietary induction of ketosis followed by re-feeding with a standard meal. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00476125
Study type Interventional
Source Beth Israel Deaconess Medical Center
Contact
Status Completed
Phase N/A
Start date March 2008
Completion date August 2023
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