Glasdegib for Chronic Graft-Versus-Host Disease

Status Terminated

Clinical Trial Summary

This phase I/II trial studies whether glasdegib is helpful in treating sclerosis associated with chronic graft-versus-host disease. It will also investigate the safety of glasdegib in treating patients with chronic graft-versus-host disease.

Clinical Trial Description

OUTLINE: This is a phase I/II study. Patients receive glasdegib orally (PO) once daily (QD) on days 1-28. Cycles repeat every 28 days for up to 24 months in the absence of disease progression or unacceptable toxicity. ;

Study Design

Related Conditions & MeSH terms

Bronchiolitis Obliterans Syndrome
Chronic Graft Versus Host Disease
Fasciitis
Graft vs Host Disease

Clinical Trial Details

NCT number	NCT04111497
Study type	Interventional
Source	Fred Hutchinson Cancer Center
Contact
Status	Terminated
Phase	Phase 1/Phase 2
Start date	December 3, 2019
Completion date	August 23, 2023

View Details

See also
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