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Hematopoietic Stem Cell Transplant for Fanconi Anemia — FA  

Fanconi Anemia Clinical Trial

Official title:
A Phase II Trial of Hematopoietic Stem Cell Transplantation for the Treatment of Patients With Fanconi Anemia Lacking a Genotypically Identical Donor, Using a Chemotherapy Only Cytoreduction With Busulfan, Cyclophosphamide and Fludarabine

Clinical Trial Summary

The trial proposed is a single arm phase II treatment protocol designed to examine engraftment, toxicity, graft-versus-host disease, and ultimate disease-free survival following a novel cytoreductive regimen including busulfan, cyclophosphamide and fludarabine and anti-thymocyte globulin (ATG- a non-chemotherapy drug whose role is to kill your immune system) for the treatment of patients with Fanconi anemia who have severe aplastic anemia (SAA), or myelodysplastic syndrome (MDS) or acute myelogenous leukemia (AML), lacking HLA-genotypically identical donors using stem cell transplants derived from (1) HLA-compatible unrelated donors or (2) HLA haplotype-mismatched related donors.

Clinical Trial Description

We are currently recruiting patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01071239
Study type Interventional
Source Medical College of Wisconsin
Contact
Status Completed
Phase Phase 2
Start date April 2009
Completion date August 30, 2016
View Details
See also
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