Misoprostol Prior to IUD Insertion in Nullipara

Status Completed

Clinical Trial Summary

The use of misoprostol at a dose of 400 µg administered vaginally four hours prior to IUD insertion increased the ease of insertion and reduced the incidence of pain during the procedure, although the frequency of cramps increased following misoprostol use.

Clinical Trial Description

Nulligravidas women of reproductive age were submitted to IUD insertion between July 2009 and November 2011 at the Instituto de Medicina Integral Prof. Fernando Figueira in Recife, Pernambuco, Brazil. A total of 179 women were randomly allocated to two groups: 86 to use 400 µg of misoprostol vaginally four hours prior to IUD insertion and 93 to use placebo. Risk ratios (RR) were calculated as measures of relative risk, together with their 95% confidence intervals (95%CI). The number needed to treat (NNT) and the number needed to harm (NNH) were also calculated. ;

Study Design

Related Conditions & MeSH terms

Family Planning

Clinical Trial Details

NCT number	NCT03490617
Study type	Interventional
Source	Instituto Materno Infantil Prof. Fernando Figueira
Contact
Status	Completed
Phase	Phase 3
Start date	July 2009
Completion date	November 2011

View Details

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