Familial Dysautonomia Clinical Trial
Official title:
Pilot Study of Dexmedetomidine Sublingual Film for the Ambulatory Treatment of Hyperadrenergic Autonomic Crisis in Patients With Familial Dysautonomia
This is a pilot open-label study to evaluate the feasibility of conducting a clinical trial using sublingual dexmedetomidine sublingual film to treat hyperadrenergic autonomic crises in patients with Familial Dysautonomia at home. The primary aims are to examine the feasibility of performing a clinical trial using dexmedetomidine at home to terminate autonomic crisis, and refine the interventions and assessments used to evaluate autonomic crisis termination.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Withdrawn |
NCT02608931 -
The Safety, Tolerability and Efficacy of Dronabinol, for the Treatment of Nausea and Vomiting in Familial Dysautonomia
|
Phase 2 | |
| Completed |
NCT02276716 -
The Nutritional Supplement Phosphatidylserine in Patients With Familial Dysautonomia
|
Phase 2 | |
| Completed |
NCT02274051 -
The Safety and Tolerability of Kinetin, in Patients With Familial Dysautonomia
|
Phase 1 | |
| Completed |
NCT01987219 -
The Effects Of Bronchodilator Therapy On Respiratory And Autonomic Function In Patients With Familial Dysautonomia
|
Phase 3 | |
| Completed |
NCT01999257 -
Efficacy Study of an Online Educational Module Before Carrier Genetic Screening in Persons of Ashkenazi Jewish Descent.
|
N/A | |
| Completed |
NCT03013777 -
A Trial of Cognitive Behavioral Therapy in Familial Dysautonomia
|
N/A | |
| Completed |
NCT01212484 -
Carbidopa for the Treatment of Nausea and Vomiting in Familial Dysautonomia
|
Phase 3 | |
| Not yet recruiting |
NCT06148311 -
Dexmedetomidine Sublingual Film for the Ambulatory Treatment of Hyperadrenergic Autonomic Crisis in Patients With Familial Dysautonomia
|
Phase 2 | |
| Withdrawn |
NCT03911063 -
Telemedicine Clinical Trial for Cognitive Behavioral Therapy in Familial Dysautonomia
|
N/A |