Concurrent Oxytocin With Membrane Sweeping Versus Dinoprostone Pessary in Labor Induction of Multiparous Women at Term

Failed Induction of Labor Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02618096
• Other study ID #: SWP_PG_M2
• Status: Completed
• Phase: N/A
• Start date: October 2015
• Est. completion date: October 2018

Study information

• Verified date: October 2016
• Source: Seoul National University Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to compare concurrent oxytocin with membrane sweeping versus dinoprostone pessary in labor induction for multiparas at term with an unfavorable cervix.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 154
• Est. completion date: October 2018
• Est. primary completion date: October 2018
• Accepts healthy volunteers: No
• Gender: Female
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• singleton pregnancy

• Multiparous women

• gestational age >=37.0 weeks

• Bishop score <=6

• intact amniotic membrane

• absence of labor

• live fetus with vertex presentation

• no previous uterine surgical procedure

Exclusion Criteria:

• Multiple pregnancy

• Placenta previa

Related Conditions & MeSH terms

• Failed Induction of Labor

Intervention

Drug:
• Oxytocin

• Dinoprostone

Procedure:
• Membrane sweeping

Locations

Country	Name	City	State
Korea, Republic of	Department of Obstetrics and Gynecology Seoul National University Bundang Hospital	Seongnam-si	Gyeonggi-do

Sponsors (1)

Lead Sponsor	Collaborator
Seoul National University Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Vaginal delivery within 24 hours	Vaginal delivery within 24 hours is defined as vaginal delivery after 24 hours of initiating intervention (i.e. membrane sweeping or dinoprostone) on the first day of induction.	From the time of initiating intervention (i.e. membrane sweeping or dinoprostone) until the time of vaginal delivery, assessed up to 24 hours
Secondary	Successful labor induction	to achieve the active phase of labor corresponding to a cervical dilatation of >=4cm	From the time of initiating intervention (i.e. membrane sweeping or dinoprostone) until the time of active phase of labor (defined as a cervical dilatation of >=4cm), assessed up to 24 hours
Secondary	Incidence of cesarean delivery		End of labor induction (assessed up to 120 hours)
Secondary	The interval from start of oxytocin to delivery		From the time of initiating oxytocin infusion until the time of delivery, assessed up to 120 hours