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NCT01537952 Clinical Trial

Microbiologic Findings of Acute Facial Palsy in Children

Facial Paralysis Clinical Trial

Official title:
Microbiologic Findings of Acute Facial Palsy in Children

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01537952
Other study ID # 230419
Secondary ID
Status Completed
Phase N/A
First received February 18, 2012
Last updated February 22, 2012
Start date May 2007
Est. completion date August 2009

Study information
Verified date February 2012
Source Helsinki University
Contact n/a
Is FDA regulated No
Health authority Finland: Ethics Committee
Study type Observational

Clinical Trial Summary

Objective: Microbiologic etiologies of facial palsy in children were investigated.

Study design: Prospective clinical study. Methods: Forty-six children aged 0-16 years with facial palsy comprised the study group. Paired serum samples and cerebrospinal fluid were tested to find indications (antibodies, growth of the microbe, or nucleic acids) of microbes putatively associated with facial palsy. The microbes tested were herpes simplex virus-1 and -2, varicella-zoster virus, human herpesvirus-6, Mycoplasma pneumoniae, Borrelia burgdorferi, influenza A and B-, picorna-, cytomegalo-, parainfluenza-, respiratory syncytial-, coxsackie B5-, adeno-, and enteroviruses, Chlamydia psittaci, and Toxoplasma gondii. Besides the routine tests in clinical practice, serum and cerebrospinal fluid samples were tested with a highly sensitive microarray assay for DNA of herpes simplex virus-1 and -2, human herpesvirus-6A , -6B, -7, Epstein-Barr-, cytomegalo-, and varicella-zoster viruses.

Recruitment information / eligibility
Status Completed
Enrollment 46
Est. completion date August 2009
Est. primary completion date August 2009
Accepts healthy volunteers No
Gender Both
Age group N/A to 16 Years
Eligibility Inclusion Criteria:

- Age 0-16

- Facial palsy

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
n/a

Sponsors (2)
Lead Sponsor Collaborator
Helsinki University Helsinki University Central Hospital
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