Clinical Trials Logo

Clinical Trial Summary

The goal of this prospective observational study is to learn about the impact of conventional eyelid correction surgery on the eye's health and function in ptosis and eyelid retraction patient. The main questions it aims to answer are: • 1. Changes in corneal topography, higher-order corneal aberrations, corneal biomechanical characteristics, and corneal epithelial thickness before and after the surgery 2. Influence of corneal refraction examinations , vision change, and tear film function after the surgery Fifty participants will undergo conventional eyelid correction surgery by the same ophthalmologist (YH Wei) and non-invasive examinations before and after the surgery. The patient will be separate to 2 groups, including 30 with correction for ptosis and 20 with correction for eyelid retraction. The research will collect information of the operated eye and fellow eye, and the data will be compared between operated and fellow eye and with the other group.


Clinical Trial Description

The position of the upper eyelid affects the health and function of the eye. Ptosis can obstruct the vision, and eyelid retraction can result in the loss of proper protection of the ocular surface. Through conventional upper eyelid correction surgery, the height of the upper eyelid can be adjusted to a proper position. However, after upper eyelid surgery, the pressure of the upper eyelid on the corneal surface may change, affecting corneal topography, higher-order corneal aberrations, corneal biomechanical characteristics, and corneal epithelial thickness. These changes may affect postoperative vision and visual quality. The impact of upper eyelid surgery on corneal refraction and corneal biomechanical characteristics remains inconclusive in current studies, and the impact on corneal epithelial thickness is even less investigated. This is a prospective observational study, expecting to enroll 50 patients who have undergone upper eyelid surgery, including 30 for ptosis correction and 20 for eyelid retraction correction. Non-invasive examinations will be used to assess changes in corneal topography, higher-order corneal aberrations, corneal biomechanical characteristics, and corneal epithelial thickness before and after the surgery to understand the impact of upper eyelid surgery on the ocular surface and the possible mechanism or influencing factors of postoperative vision changes. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05750251
Study type Observational [Patient Registry]
Source National Taiwan University Hospital
Contact Yi-Hsuan Wei, PhD
Phone +886-2312-3456
Email ericwei224@hotmail.com
Status Recruiting
Phase
Start date February 6, 2023
Completion date June 30, 2024

See also
  Status Clinical Trial Phase
Completed NCT01190397 - Warming Efficiency of Warm Compresses Versus BLEPHASTEAM® in Eyelid Therapy Phase 1
Withdrawn NCT05672407 - The Role of Local Tranexamic Acid on Periorbital Oculoplastic Surgery Phase 4
Completed NCT03199911 - Topical Antibiotic Prophylaxis for Eyelids Phase 4
Recruiting NCT04689230 - Small Incision Technique Versus Upper Blepharoplasty in Upper Eyelid Medial Pad Fat Removal N/A
Completed NCT01091311 - Evaluation of Satisfaction Regarding Patient's Management of Ocular Surface Diseases Phase 4
Recruiting NCT04359979 - Tamsulosin for Thyroid Lid Retraction N/A
Recruiting NCT04102878 - Transconjunctival vs Transcutaneous Anaesthesia in Oculoplastics N/A
Completed NCT01189474 - Evaluation of Satisfaction Regarding Patient's Management of Ocular Surface Diseases Phase 4
Active, not recruiting NCT04149210 - FLuorometholone as Adjunctive MEdical Therapy for TT Surgery (FLAME) Trial Phase 3
Not yet recruiting NCT04235803 - Telemedicine Follow-up for Routine, Low-Risk Oculoplastic Surgery N/A
Completed NCT04554329 - Bandage Contact Lenses Versus Eye Patching of Müller's Muscle-conjunctival Resection N/A
Recruiting NCT04898933 - Patient Satisfaction After Eyelid Lesion Excision
Recruiting NCT04861454 - Brassiere Brow Suture and Internal Browpexy
Recruiting NCT04201925 - Functional Changes After Upper Blepharoplasty
Recruiting NCT04255667 - Eyelid Crush for Marginal Eyelid Surgery
Recruiting NCT05016362 - Medial Fat Pad Preservation in Upper Eyelid Blepharoplasty
Recruiting NCT05945069 - Feasibility of Dynamic Muscle Stimulation + Radiofrequency for Improving Blink Quality in Subjects With Dry Eye Disease N/A
Recruiting NCT04140734 - Spacer Graft Study N/A
Recruiting NCT04720586 - Surgical Treatment of Lower Eyelid Involutional Entropion and Dermatochalasis N/A
Recruiting NCT04921020 - Assessment of Eyelid Topology and Kinetics Based on Deep Learning Method