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Eye Infections, Bacterial clinical trials

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NCT ID: NCT00357539 Completed - Clinical trials for Eye Infections, Bacterial

Safety and Ocular Pharmacokinetics After 1 Drop of T1225 0.5, 1 and 1.5% in 48 Healthy Volunteers

Start date: February 2002
Phase: Phase 1
Study type: Interventional

To compare the ocular tolerance, safety and ocular pharmacokinetics of 3 concentrations (0.5% - 1.0% - 1.5%) and the vehicle of T1225.

NCT ID: NCT00357383 Completed - Clinical trials for Eye Infections, Bacterial

Study of the Ocular Safety After Repeated Instillations of T1225 1% or 1.5% Eye Drops in Healthy Volunteers

Start date: October 2002
Phase: Phase 1
Study type: Interventional

To evaluate the ocular tolerance of T1225 1% and 1.5% eye drops versus vehicle after one instillation twice-daily (morning and evening), in one eye, during 3 days (from Day 0 to Day 2). To assess azithromycin tear, conjunctiva and plasmatic concentrations, after a 3-day treatment period

NCT ID: NCT00357292 Completed - Clinical trials for Eye Infections, Bacterial

Ocular Tolerance, Safety and Ocular Pharmacokinetics After 1 Drop of T1225 0.5, 1.0, 1.5% in 48 Healthy Volunteers

Start date: March 2002
Phase: Phase 1
Study type: Interventional

To compare the ocular tolerance, the safety and the ocular pharmacokinetics of 3 concentrations (0.5% - 1.0% - 1.5%) and the vehicle of T1225 after one drop instillation

NCT ID: NCT00356850 Completed - Clinical trials for Eye Infections, Bacterial

Ocular Pharmacokinetics After a Single Drop Instillation of T1225 0.5, 1, 1.5% in 91 Healthy Volunteers

Start date: May 2002
Phase: Phase 1
Study type: Interventional

To evaluate azithromycin tear concentrations after instillation of one drop of one of the three T1225 concentrations (0.5%, 1% and 1.5%) and to evaluate the ocular safety.

NCT ID: NCT00356772 Completed - Clinical trials for Eye Infections, Bacterial

Azithromycin Level in Tears and in Conjunctiva in 36 Healthy Volunteers

Start date: February 2003
Phase: Phase 1
Study type: Interventional

To evaluate azithromycin ocular conjunctiva concentrations 7 and 14 days after treatment initiation. To assess ocular and systemic tolerance/safety and azithromycin tear concentrations on Day 7

NCT ID: NCT00324168 Completed - Corneal Ulcer Clinical Trials

Steroids for Corneal Ulcers Trial

SCUT
Start date: September 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether adding topical steroids improves the outcomes of bacterial corneal ulcers, especially visual acuity.