Intravitreal Microplasmin in Patients Undergoing Surgical Vitrectomy

Status Completed

Clinical Trial Summary

The purpose of this trial is to evaluate the safety and preliminary efficacy of different doses and several exposure times of intravitreal microplasmin in the setting of pars plana vitrectomy for vitreomacular traction maculopathy.

Clinical Trial Description

Study drug will be administered in the mid-vitreous by injection. Patients will be enrolled into the cohorts in a sequential dose/time-escalating fashion. To ensure that enrolment is evenly balanced across eligible conditions, enrolment of any specific underlying disease type into any cohort will be capped at five (5) patients. ;

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Eye Diseases
Vitreomacular Traction Maculopathy

Clinical Trial Details

NCT number	NCT00123279
Study type	Interventional
Source	ThromboGenics
Contact
Status	Completed
Phase	Phase 2
Start date	December 2004
Completion date	November 2008

View Details

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