Clinical Trials Logo

Clinical Trial Summary

Because Propofol is the primary "anesthetic agent," and inhalational agents remain in trace quantities at the end of the procedure Sevoflurane initiated intravenous anesthesia (SIIVA) or not present at all Total intravenous anesthesia (TIVA) it is likely that different criteria may be predictive of extubation success in these patients compared to inhalational anesthesia.


Clinical Trial Description

This is because these anesthetic regimens have different pharmacologic mechanisms of actions, and therefore interact with central nervous system in different ways leading to potentially the need for different extubation criteria in patients receiving TIVA or SIIVA. Additionally, intravenous agents likely have less of an effect on airway reflexes and ventilation at light levels of anesthesia. This study is proposing an observational study to examine the predictive value of various extubation criteria in the setting of SIIVA and TIVA. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05837936
Study type Observational
Source Wake Forest University Health Sciences
Contact Wes Templeton, MD
Phone 336-716-4498
Email ttemplet@wakehealth.edu
Status Recruiting
Phase
Start date March 28, 2023
Completion date March 2028

See also
  Status Clinical Trial Phase
Completed NCT06249659 - Impact of Extubation Location After Surgery on Perioperative Times
Completed NCT03468036 - Intratracheal Suctioning and Oxygenation at Extubation
Not yet recruiting NCT05751603 - Effectiveness on Smooth Extubation According to the Administration Time of Sugammadex N/A
Completed NCT03681626 - Does Tracheal Suction During Extubation in Intensive Care Unit Decrease Functional Residual Capacity N/A
Unknown status NCT00814853 - Electrical Activity of the Diaphragm During Extubation Readiness Testing N/A
Recruiting NCT04596735 - Extubation Criteria in Patients Greater Than 59 Years of Age
Completed NCT01237886 - Weaning And Variability Evaluation N/A
Completed NCT01086995 - Weaning And Variability Evaluation (WAVE) N/A
Completed NCT03185962 - Predictors Of Successful Extubation in Critically Ill Patients: Multicentre Observational Study
Completed NCT04231890 - Early Identification and Prevention of Extubation Failure in Adults Using Integrated Pulmonary Index N/A
Recruiting NCT04036175 - Comparison of Patient Work of Breathing and Tidal Volumes With High Flow Nasal Cannula Oxygen Therapy and NIV (Non-Invasive Ventilation) After Extubation in the ICU. N/A
Completed NCT03479047 - Diaphragmatic Ultrasound Associated With RSBI Predict Weaning Issue: the Rapid Shallow Diaphragmatic Index (RSDI) N/A
Recruiting NCT05295095 - Does Positive Pressure Extubation Reduce Postoperative Desaturation? N/A
Recruiting NCT03929328 - Effect of High Flow Oxygen Therapy in Spontaneous Breathing Trial on Weaning in Mechanical Ventilated Patients N/A
Completed NCT04227639 - T-piece Versus Pressure-support for the Spontaneous Breathing Trial N/A
Completed NCT03580993 - Lung and Heart USG for Predicting Weaning in Neurosurgical Patients
Completed NCT01774292 - Effect of Intracuff Alkalinized Lidocaine on Coughing Incidence at Extubation Phase 4
Completed NCT00448565 - Prediction of Extubation Success by the Patient N/A
Completed NCT03715257 - Evaluation of Advanced Extubation Techniques in Bariatric Surgery N/A
Not yet recruiting NCT05626153 - Anesthesia Quality Improvement and Patients With Planned ICU Admission N/A