Chinese Neonatal Extracorporeal Life Support Registry (Chi-NELS)

Status Withdrawn

Clinical Trial Summary

Extracorporeal life support (ECLS), also known as extracorporeal membrane oxygenation (ECMO), is an extracorporeal technique which provides respiratory and cardiac support to patients with respiratory and/or heart failure. Neonates account for a significant proportion of patients requiring ECLS support. While with unique pathophysiology among newborn infants, neonatal ECLS treatment faces different challenges (such as specific indications, anticoagulation, hemodynamic management, high incidences of complications, ect.) from those of elder children or adults. Though neonatal ECMO has been used in developed countries since 1970s, the introduction of neonatal ECMO in China was not reported until 2010s. While on the other hand, there has been a rapid increase of neonatal ECLS cases and centers in China in the past decade with a huge variation of numbers of cases and quality among different centers. Therefore, there is an urgent need to monitor the use and quality of neonatal ECLS in China. The goal of the Chinese Neonatal Extracorporeal Life Support Registry (Chi-NELS) is to maintain a registry of use of ECLS in active neonatal ECLS centers across China, to support quality improvement of neonatal ELCS, clinical research and regulatory agencies.

Clinical Trial Description

This study aims to establish a neonatal ECLS network of all active ECLS centers in China to facilitate standardization of care and collaborative research. On the basis of the network, this prospective comprehensive registry will enroll all neonates who receive ECLS support in participating centers. The indications, managements, complications and outcomes of neonatal ECLS in China will be described in detail, to monitor the development of neonatal ECLS in China, to identify targets for quality improvement, to assist in reducing mortality and morbidity of neonates requiring ECLS support, and to facilitate innovative clinical researches. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05085080
Study type	Observational [Patient Registry]
Source	Children's Hospital of Fudan University
Contact
Status	Withdrawn
Phase
Start date	January 1, 2024
Completion date	December 31, 2025

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT00951860` - Assessment of Autonomic Maturation in Neonatal Period and Early Neural Development From a Longitudinal Prospective Cohort	N/A
Recruiting	`NCT05601375` - Speckle Tracking Echocardiography in Infants, Prenatally and Postnatally
Terminated	`NCT04025021` - Targeted Breast Milk Fortification for Very Low Birth Weight Infants in the NICU	N/A
Recruiting	`NCT05965830` - Comparing Electromyography of the Diaphragm With Ultrasound in Neonates and Children With Respiratory Support
Completed	`NCT04904965` - Frontal Electroencephalography of Neonatal Patients Under Sedation With Opioids and General Anesthesia With Propofol.	N/A
Recruiting	`NCT05835817` - Magnetoencephalography by Optical Pumping Magnetometer	N/A
Recruiting	`NCT04905732` - Nasal High-frequency Oscillatory Ventilation (NHFOV) for Ventilated Newborn Infants With BPD	N/A
Completed	`NCT04794881` - Repeat Lumbar Puncture at 24 Versus 48 Hours After Traumatic Lumbar Puncture in Neonates	N/A
Completed	`NCT05296668` - Cuffed Versus Uncuffed Tracheal Tubes in Neonates Undergoing Elective Surgery	N/A
Recruiting	`NCT04795453` - Assessment of Score System of Surgery in Necrotizing Enterocolitis(NEC) Patients
Completed	`NCT03103022` - Combination of Acetaminophen and Ibuprofen in the Management of Patent Ductus Arteriosus	Phase 1
Completed	`NCT05197868` - Applied Forces During Neonatal Intubation	N/A
Withdrawn	`NCT05075486` - Quality Improvement to Reduce Mortality or Severe Intracranial Hemorrhage in Neonatal Extracorporeal Life Support	N/A
Withdrawn	`NCT05045092` - A Follow-up Study of Neonates Receiving Extracorporeal Life Support in China
Recruiting	`NCT05181423` - Identification of Noninvasive Biomarkers for Neonates Undergoing Abdominal Surgery
Completed	`NCT05104255` - Neonatal Outcomes in Twin Pregnancies
Completed	`NCT03082001` - Sucrose to Reduce Pain During Initiation of Venipuncture in Extremely Low Birth Weight Babies	Phase 3
Not yet recruiting	`NCT05934682` - Latin American Surgical Outcomes Study in Pediatric Patients
Completed	`NCT04937348` - Visfatin and Omentin-1 - Markers of Nutritional Status of Newborns Born to Diabetic Mothers.
Completed	`NCT04464057` - Safety and Effectiveness of Early Feeding After Bowel Anastomosis in Neonates or Infants	N/A