Extubation of Patients on ECLS is Associated With a Reduction in Complications Related to Mechanical Ventilation: Retrospective Single-centre Study

Extra-Corporeal Life Support Clinical Trial

— EXTUB ECLS  

Official title:

Extubation of Patients on ECLS is Associated With a Reduction in Complications Related to Mechanical Ventilation: Retrospective Single-centre Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03295357
• Other study ID #: LAMIREL-GIRARD 2016
• Status: Completed
• Phase: N/A
• First received: September 25, 2017
• Last updated: September 25, 2017
• Start date: May 2016
• Est. completion date: December 2016

Study information

• Verified date: September 2017
• Source: Centre Hospitalier Universitaire Dijon
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

There are no clear recommendations concerning the management of patients on ECLS (Extra-Corporeal Life Support). Many teams keep patients sedated until removal of the ECLS so as to avoid accidents, notably decannulation. Moreover, there are few publications on the subject, all the more so as the extubation of patients on ECLS (Extra-Corporeal Life Support) is a recent practice. Nonetheless, it is becoming more and more frequent in the cardiovascular ICU of Dijon University Hospital. We therefore wished to evaluate the benefits of this practice by comparing 2 populations: those with extubation while on ECLS (Extra-Corporeal Life Support) and those without.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: December 2016
• Est. primary completion date: December 2016
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Patients over 18 years who were placed on ECLS between 1/01/14 and 31/12/15

Exclusion Criteria:

• Patients under 18 years old

• Patients on ECLS for a heart transplant

• Patients who died within the first 48 hours following the initiation of ECLS

Related Conditions & MeSH terms

• Extra-Corporeal Life Support

Locations

Country	Name	City	State
France	Chu Dijon Bourogne	Dijon

Sponsors (1)

Lead Sponsor	Collaborator
Centre Hospitalier Universitaire Dijon

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Incidence of VAP (ventilator-associated pneumonia) during hospitalisation in the ICU		At baseline