Exercise Clinical Trial
Official title:
Intranasal Cocaine and Temperature Regulation During Exercise
Assess the effects of intranasal cocaine on temperature regulation and whole-body sweat rate during exercise in warm environmental conditions.
Previously it was shown that intranasal cocaine attenuates skin blood flow and sweating responses during passive heat stress, when compared to placebo. However, nothing is known about the effects of cocaine on whole-body temperature regulation during mild to moderate exercise in warm environmental condition. This project will test the hypothesis that intranasal cocaine attenuates whole-body sweat rate, resulting in greater elevations in core temperature during mild to moderate exercise in warm environmental conditions. Primary data include core temperature, skin temperatures, and whole body sweat rate. Secondary variables include cardiovascular responses, perceptions of exercise exertion and thermal comfort, and metabolic heat production. Intranasal lidocaine will be used as the placebo for cocaine. The selection of the drug administered during the first experimental trial will be randomized, with the other drug administered during the second experimental trial. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05156424 -
A Comparison of Aerobic and Resistance Exercise to Counteract Treatment Side Effects in Men With Prostate Cancer
|
Phase 1/Phase 2 | |
| Completed |
NCT05108181 -
Muscle Typology and Strength Training Adaptations
|
N/A | |
| Recruiting |
NCT05052918 -
The Effect of Exercise and Metformin on Carotid Intima-media Thickness in Patients With Prediabetes
|
N/A | |
| Completed |
NCT04508270 -
Significance of Early Mobilization After VATS-L
|
||
| Recruiting |
NCT04994340 -
Physical Activity Observatory of Castilla-La Mancha
|
||
| Completed |
NCT04815980 -
Impact of Pilates on Running Mechanics
|
N/A | |
| Completed |
NCT05189795 -
The Construction of Physical ACtivity Enhancement Scheme (PACES) in Hemodialysis Patients
|
||
| Completed |
NCT03683758 -
Effects of the FIFA11+ Warm-up Program on Speed, Agility, and Vertical Jump Performance in Adult Female Amateur Soccer Players
|
N/A | |
| Completed |
NCT05538520 -
Effects of Pilates Stretching on Flexibility, Strength, Power and Muscular Endurance
|
N/A | |
| Completed |
NCT06315036 -
Effects of Developmental Gymnastics on Preschoolers' Motor Skills
|
N/A | |
| Completed |
NCT03171064 -
Exercise as a Supportive Measure for Patients Undergoing Checkpoint-inhibitor Treatment
|
Phase 2 | |
| Recruiting |
NCT05496751 -
Response Variability to Exercise
|
N/A | |
| Not yet recruiting |
NCT05029804 -
Effect of Walking Exercise Training on Adherence to Disease Management and Metabolic Control in Diabetes
|
N/A | |
| Completed |
NCT04207359 -
Effects of Creatine Supplementation in Breast Cancer Survivors
|
N/A | |
| Completed |
NCT03832205 -
Validation of Respiratory Rate and Heart Rate Measurements by Capaciflectors Placed in Four Locations on the Chest
|
||
| Completed |
NCT04099654 -
The Effect of Core Stabilization Exercise Program in Obese Subjects Awaiting Bariatric Surgery
|
N/A | |
| Completed |
NCT03477188 -
The Effects of Somatosensory and Vestibular Rehabilitation Additional Conventional Therapy on Balance in Patients With Acute Stroke.
|
N/A | |
| Completed |
NCT03297567 -
Physical Therapy Guidelines For Hospitalized Elderly
|
N/A | |
| Recruiting |
NCT05956327 -
Insight Into Hippocampal Neuroplasticity in Schizophrenia by Investigating Molecular Pathways During Physical Training
|
N/A | |
| Recruiting |
NCT06018311 -
Exercising Together for Hispanic Prostate Cancer Survivor-Caregiver Dyads
|
N/A |