Exercise Clinical Trial
Official title:
Postexercise Central Blood Pressure and Hemodynamic Response After Continuous and Aerobic Interval Exercise
The purpose of this study is to examine the acute effect of continuous and aerobic interval exercise on postexercise central BP response in men with an elevated blood pressure.
The specific aim of this study is to compare postexercise central blood pressure after
continuous and aerobic interval exercise. It is hypothesized that aerobic interval exercise
will produce a longer duration postexercise hypotensive response compared to continuous
exercise. 14 healthy, inactive (defined as less than 60 minutes of moderate to vigorous
physical activity per week, as characterized by accelerometry) men aged 18-45 yr, who have
high normal BP or stage 1 hypertension (systolic BP (SBP) 120-159 mmHg or diastolic BP (DBP)
80-99 mmHg) according to JNC 8 established guidelines, will be included in this randomized
cross-over design study. Each subject will complete three conditions in a randomized order:
aerobic interval exercise, continuous exercise, and non-exercise control.
For the aerobic interval exercise condition, subjects will be equipped with a heart rate (HR)
monitor and asked to perform an interval exercise bout on a cycle ergometer. To warm up,
subjects will cycle at a work rate associated with 50% HRmax for 10 minutes. Wattage will
then increase and subjects will do four 4-minute intervals at a work rate associated with
90%-95% HRmax, separated by 3 minutes of active recovery at a work rate associated with 50%
HRmax. Subjects will be given a 5-minute cool-down period at a work rate associated with 50%
HRmax. After the exercise, subjects will remain in the lab for 4 hours and their blood
pressure will be measured every 10 minutes using the Oscar 2 with SphygmoCor ambulatory blood
pressure system, and cardiac output measured in 10-second averages using the PhysioFlow.
During this time, subjects will remain seated with their body posture maintained constant.
For the continuous exercise condition, subjects will be equipped with a HR monitor and asked
to perform a continuous exercise bout on a cycle ergometer. To warm up, subjects will cycle
at a work rate associated with 50% HRmax for 10 minutes. Wattage will then increase and
subjects will perform a 30-minute exercise bout at a HR that elicits 75%-80% of their
measured HRmax. Work rate will be adjusted, if needed, to keep HR within this value. Subjects
will be given a 5-minute cool-down period at a work rate associated with 50% HRmax. After the
exercise, subjects will remain in the lab for 4 hours and their blood pressure will be
measured every 10 minutes using the Oscar 2 with SphygmoCor ambulatory blood pressure system,
and cardiac output measured in 10-second averages using the PhysioFlow. During this time,
subjects will remain seated with their body posture maintained constant.
For the non-exercise control condition, subjects will be asked to come to the laboratory for
4 hours and have their blood pressure will be measured every 10 minutes using the Oscar 2
with SphygmoCor ambulatory blood pressure system, and cardiac output measured in 10-second
averages using the PhysioFlow. During this time, subjects will remain seated with their body
posture maintained constant.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05156424 -
A Comparison of Aerobic and Resistance Exercise to Counteract Treatment Side Effects in Men With Prostate Cancer
|
Phase 1/Phase 2 | |
Completed |
NCT05108181 -
Muscle Typology and Strength Training Adaptations
|
N/A | |
Recruiting |
NCT05052918 -
The Effect of Exercise and Metformin on Carotid Intima-media Thickness in Patients With Prediabetes
|
N/A | |
Completed |
NCT04508270 -
Significance of Early Mobilization After VATS-L
|
||
Recruiting |
NCT04994340 -
Physical Activity Observatory of Castilla-La Mancha
|
||
Completed |
NCT04815980 -
Impact of Pilates on Running Mechanics
|
N/A | |
Completed |
NCT05189795 -
The Construction of Physical ACtivity Enhancement Scheme (PACES) in Hemodialysis Patients
|
||
Completed |
NCT03683758 -
Effects of the FIFA11+ Warm-up Program on Speed, Agility, and Vertical Jump Performance in Adult Female Amateur Soccer Players
|
N/A | |
Completed |
NCT05538520 -
Effects of Pilates Stretching on Flexibility, Strength, Power and Muscular Endurance
|
N/A | |
Completed |
NCT06315036 -
Effects of Developmental Gymnastics on Preschoolers' Motor Skills
|
N/A | |
Completed |
NCT03171064 -
Exercise as a Supportive Measure for Patients Undergoing Checkpoint-inhibitor Treatment
|
Phase 2 | |
Recruiting |
NCT05496751 -
Response Variability to Exercise
|
N/A | |
Not yet recruiting |
NCT05029804 -
Effect of Walking Exercise Training on Adherence to Disease Management and Metabolic Control in Diabetes
|
N/A | |
Completed |
NCT04207359 -
Effects of Creatine Supplementation in Breast Cancer Survivors
|
N/A | |
Completed |
NCT03832205 -
Validation of Respiratory Rate and Heart Rate Measurements by Capaciflectors Placed in Four Locations on the Chest
|
||
Completed |
NCT04099654 -
The Effect of Core Stabilization Exercise Program in Obese Subjects Awaiting Bariatric Surgery
|
N/A | |
Completed |
NCT03297567 -
Physical Therapy Guidelines For Hospitalized Elderly
|
N/A | |
Completed |
NCT03477188 -
The Effects of Somatosensory and Vestibular Rehabilitation Additional Conventional Therapy on Balance in Patients With Acute Stroke.
|
N/A | |
Recruiting |
NCT05956327 -
Insight Into Hippocampal Neuroplasticity in Schizophrenia by Investigating Molecular Pathways During Physical Training
|
N/A | |
Recruiting |
NCT06018311 -
Exercising Together for Hispanic Prostate Cancer Survivor-Caregiver Dyads
|
N/A |