Physiological Characteristics of High Altitude Climbers

Exercise Clinical Trial

— ALTIPERF  

Official title:

Physiological Characteristics of High Altitude Climbers

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02880150
• Other study ID #: 2013-A00629-36
• Secondary ID: ALTIPERF
• Status: Completed
• Phase: N/A
• First received: October 21, 2013
• Last updated: August 22, 2016
• Start date: May 2013
• Est. completion date: May 2014

Study information

• Verified date: August 2016
• Source: University Hospital, Grenoble
• Contact: n/a
• Is FDA regulated: No
• Health authority: France: Direction Générale de la Santé
• Study type: Interventional

Clinical Trial Summary

Climbing at high altitude and tolerating hypoxic environment require specific physiological adaptations. Large intersubjects differences exist regarding the ability to adapt to high altitude and hypoxia. The present study aims to characterise the physiological responses to hypoxia in a group of elite climbers by comparison to sea level athletes. We hypothesised that elite climbers would show better physiological responses to hypoxia and more preserved performances compared to sea level.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 20
• Est. completion date: May 2014
• Est. primary completion date: March 2014
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

• Age between 18 and 40

• Member of the national high altitude climbing group

Exclusion Criteria:

• Any diseases incompatible with hypoxic exposure, exercise testing

• Pregnancy

Study Design

Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Health Services Research

Related Conditions & MeSH terms

• Exercise
• Hypoxia
• Sport Performance

Intervention

Other:
• Stress test

Locations

Country	Name	City	State
France	Grenoble University Hospital	Grenoble

Sponsors (2)

Lead Sponsor	Collaborator
University Hospital, Grenoble	Institut National de la Santé Et de la Recherche Médicale, France

Country where clinical trial is conducted

France, 

References & Publications (1)

Verges S, Rupp T, Jubeau M, Wuyam B, Esteve F, Levy P, Perrey S, Millet GY. Cerebral perturbations during exercise in hypoxia. Am J Physiol Regul Integr Comp Physiol. 2012 Apr 15;302(8):R903-16. doi: 10.1152/ajpregu.00555.2011. Epub 2012 Feb 8. Review. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Performance reduction in hypoxia versus normoxia	Difference in maximal cycling power output between the normoxic and the hypoxic exercise test	Day one on the evaluation day	No
Secondary	Near infrared signals during exercise	Differences in cerebral and muscle TOI during exercise between the normoxia and the hypoxic exercise	Day one on the evaluation day	No