The Body's Response to Aerobic Versus Resistance Exercise

Exercise Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00761163
• Other study ID #: 0701004892
• Secondary ID: NIH/NIA 5R01AG02
• Status: Completed
• Phase: N/A
• First received: September 25, 2008
• Last updated: January 16, 2013
• Start date: February 2007
• Est. completion date: November 2008

Study information

• Verified date: January 2013
• Source: Purdue University
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to identify the body's response to aerobic vs. resistance exercise. Throughout this study, we will examine food intake, appetite, and physical and mental well-being before, during, and after aerobic and resistance exercise.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 25
• Est. completion date: November 2008
• Est. primary completion date: November 2008
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Body mass index between 18-29 kg/m2

• Weight stable (< 4.5 kg weight change within last 6 months)

• Non-smoking

• Constant habitual activity patterns within last 3 months

• Non-diabetic

• Resistive exercise training (= 2 times a week) based on reported physical activity levels (questionnaire)

• Aerobic exercise training (= 2 times a week, 30-min sessions) based on reported physical activity levels (questionnaire)

• Confirmation of acceptability of eating the study test foods (macaroni casserole)

• Approved to participate in this study by our study physician and principle investigator

The older subjects must also meet the following eligibility criteria:

• Age range: 65 years and older

• Body fat (women: <38%; men: <28%)

• Normal resting EKG as assessed by a Cardiologist

The younger subjects must also meet the following eligibility criteria:

• Age range: 18-29 years

• Body fat (women: <28%; men: <18%)

Exclusion Criteria:

• Body mass index: outside of the 18-29 kg/m2 range

• Gained or lost > 4.5 kg within the last 6 months

• Smoker (currently or within the last year)

• Intermittently been involved in a diet and/or exercise program within the last 3 months

• Clinically diagnosed as diabetic

• Did not perform resistive exercise training (currently or within the last 3 months) based on reported physical activity levels (questionnaire)

• Did not perform adequate aerobic exercise (currently or within the last 3 months) based on physical activity levels (questionnaire)

• Study food is found to be unacceptable for consumption by the subject

• Unapproved to participate in this study by our study physician and principle investigator

The older subjects:

• Age range: <65 yrs

• Body fat (women: >38%; men: >28%)

• Abnormal resting EKG (interpreted by a cardiologist) and assessed (for study exclusion) by our study physician, Arthur Rosen, MD

The younger subjects:

• Age range: outside the >29 yrs or <18 yrs

• Body fat (women: >28%; men: >18%)

Study Design

Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

• Exercise

Intervention

Other:
• Resistance Exercise
The subjects will complete 2 resistive exercise sessions on non-consecutive days that will be supervised by our laboratory staff. The following exercises will be performed using the Keiser Sports Health equipment in Ismail Health, Exercise, and Nutrition Center: seated row, double leg press, seated leg curl, chest press, and leg extension. The subjects will individually perform 3 sets of 8-10 repetitions at an exercise intensity of 70% of pre-determined maximal strength for these exercises. Each repetition will be performed in a slow (six to eight seconds) uniform fashion, giving equal time to the concentric (muscle shortening) and eccentric (muscle lengthening) portions. One minute of rest will be allowed between sets. The last repetition of the third set of each exercise will be done to voluntary fatigue or the performance of 12 repetitions.
• Aerobic Exercise
The subjects will complete 2 aerobic exercise sessions on non-consecutive days that will also be supervised by our laboratory staff. The subjects will perform 45 minutes of aerobic exercise on a stationary bike at an exercise intensity of 70% of their heart-rate reserve.
• Control (Non-exercise)
The subjects will also complete 2 non-exercise sessions on non-consecutive days that will also be supervised by our laboratory staff. These sessions will consist of incorporating diversionary tasks throughout a 45 minute period consisting of a variety of motor and psychological tasks (tests of hand steadiness, alertness, optical illusions, mental acuity, etc.)

Locations

Country	Name	City	State
United States	Purdue University	West Lafayette	Indiana

Sponsors (1)

Lead Sponsor	Collaborator
Purdue University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Physical well being via electrocardiogram and body composition		5-6 weeks	No
Primary	Mental well being via questionnaires		5-6 weeks	No