Muscle Glycogen Synthesis When Caffeine and Protein is Co-Ingested With Carbohydrates

Exercise Recovery Clinical Trial

Official title:

The Effect of Caffeine or Protein Co-ingestion With Carbohydrate on Post-exercise Muscle Glycogen Synthesis Rate.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00975390
• Other study ID #: 08-3-066
• Status: Completed
• Phase: N/A
• First received: September 10, 2009
• Last updated: April 13, 2015
• Start date: February 2009
• Est. completion date: September 2009

Study information

• Verified date: April 2015
• Source: Maastricht University Medical Center
• Contact: n/a
• Is FDA regulated: No
• Health authority: Netherlands: Medical Ethics Review Committee (METC)
• Study type: Interventional

Clinical Trial Summary

The aim of the present study is to investigate the effect of added protein+leucine or caffeine to 1.2 g/kg/h CHO on the rate of post-exercise muscle glycogen re-synthesis in healthy, recreational athletes.

The investigators hypothesize that both interventions (the addition of caffeine or protein+leucine) will lead to higher glycogen re-synthesis compared to the ingestion of CHO only, and that the co-ingestion of protein and leucine will result in the highest muscle glycogen synthesis rates.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 14
• Est. completion date: September 2009
• Est. primary completion date: September 2009
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• male cyclists

• healthy

• BMI < 25

Exclusion Criteria:

• female

• use of medication

• non cycling

• BMI > 25

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Basic Science

Related Conditions & MeSH terms

• Exercise Recovery

Intervention

Dietary Supplement:
• Carbohydrate
1.2 g/kg/h
• Carbohydrate and protein ingestion
1.2 g/kg/h carbohydrate plus 0.4 g/kg/h protein
• Carbohydrate and caffeine ingestion
1.2 g/kg/h carbohydrate and 1.67 g/kg/h caffeine

Locations

Country	Name	City	State
Netherlands	Maastricht University	Maastricht

Sponsors (1)

Lead Sponsor	Collaborator
Maastricht University Medical Center

Country where clinical trial is conducted

Netherlands, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Muscle glycogen synthesis rates		6 hours	No
Secondary	Glycogen synthase activity, plasma glucose, insulin, free fatty acids and epinephrine responses		6 hours	No