Exercise Performance Clinical Trial
Official title:
The Impact of Acute (2 h) and Short-term (4 Days) Nitrate Supplementation in the Form of Red Beet Root Juice on Intense Intermittent Exercise Performance.
Both acute ingestion (1-3 h) and chronic supplementation (3-30 days) with dietary nitrate has
been shown to increase nitric oxide activity and, in some studies, to improve exercise
economy, exercise tolerance, and endurance exercise performance. In addition, more recent
evidence suggests that dietary nitrate has the potential to enhance team-sport-specific
high-intensity intermittent exercise performance. Indeed, chronic dietary nitrate
supplementation (2-6 days) has been reported to increase the distance covered before
exhaustion during the Yo-Yo intermittent recovery level 1 test, a well-established and
ecologically valid test widely used to mimic the high-intensity running bouts of soccer
match-play. However, while these findings suggest that nitrate may be an effective ergogenic
aid for team-sport players when consumed daily, it is currently unclear if the improvement in
team-sport specific intermittent exercise performance can be achieved following a single
bolus of dietary nitrate. Given the increasing interest and use of dietary nitrate as an
ergogenic aid by team-sport players, establishing the shortest period of supplementation
required to elicit an ergogenic effect is important in order to guide athletes on optimal
supplementation strategies.
Given that a single bolus of dietary nitrate has previously been shown to improve exercise
tolerance and endurance exercise performance, and an improved Yo-Yo IR1 performance has been
observed after chronic nitrate supplementation, the investigator hypothesizes that acute (2
h) and short-term (4 days) nitrate supplementation will significantly elevate nitric oxide
activity (measured as an increase in plasma nitrite concentration and skeletal muscle nitrate
concentration) and improve performance during the Yo-Yo IR1 test (measured as an increased in
distance covered (m) during the test at the point of volitional exhaustion) to a similar
extent, when compared to a placebo.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03294642 -
Potato Ingestion and Time-trial Performance
|
N/A | |
Completed |
NCT05831527 -
An Exploratory Investigation of a Supplement to Promote Gut Health
|
N/A | |
Not yet recruiting |
NCT03954665 -
Ketone Supplementation and Exercise Performance
|
N/A | |
Completed |
NCT04263246 -
Medium-Term Supplementation With Herbal Extract for Exercise Performance and Antioxidant Status
|
N/A | |
Not yet recruiting |
NCT05428228 -
Clinical Study to Evaluate the Effects of Two Novel Hydration Beverage Formulas on Rehydration in Healthy Adults
|
N/A | |
Recruiting |
NCT04004676 -
Ketone Supplementation, Glycogen Replenishment and Time Trial Performance Following Glycogen Lowering Exercise
|
N/A | |
Completed |
NCT03565523 -
The Effect of Dietary Nitrate Supplementation on Linear Running Sprint Performance, Agility and Vertical Jump Performance in a Rested and Fatigued State
|
N/A | |
Recruiting |
NCT06066606 -
U-LABA/ICS Effects on Exercise Performance, Vilanterol
|
N/A | |
Recruiting |
NCT06067100 -
U-LABA/ICS Effects on Exercise Performance, Indacaterol
|
N/A | |
Recruiting |
NCT06077019 -
Role of Lung Function for Exercise Capacity in Well-trained Individuals
|
N/A | |
Completed |
NCT05559372 -
Energy Drink Effects on Performance, Mood, and Cardiovascular Outcomes
|
N/A | |
Completed |
NCT03525561 -
Acetazolamide and Exercise Performance at Altitude
|
Early Phase 1 | |
Completed |
NCT03929575 -
Effects of Herbal Supplements on Endurance Exercise Performance
|
N/A | |
Completed |
NCT03977246 -
Effect of Open-placebo Intervention on Cycling Performance
|
N/A | |
Completed |
NCT03686982 -
The Impact of Supplementation With Novel Prototype Nutrition Bar on Nitric Oxide Bioavailability and Measures of Athlete Performance
|
N/A | |
Completed |
NCT06165523 -
Kefir Versus Milk on Time-Trial Performance in Masters Athletes
|
N/A | |
Completed |
NCT06390670 -
The Effect of Colostrum Bovinum Supplementation in Endurance Athletes
|
Phase 2/Phase 3 | |
Completed |
NCT05586295 -
Vitamin B Complex Improved Exercise Performance and Anti-fatigue
|
N/A | |
Recruiting |
NCT06374641 -
The Effects of a Novel Mitochondrial Substrate Supplement on Exercise Performance and Cognitive Function
|
N/A | |
Completed |
NCT05841407 -
Beetroot Supplementation and High Intensity Exercise
|
N/A |