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Cognition in Allogeneic Stem Cell Transplanted Patients and Sports — CaSpo  

Allogeneic Stem Cell Transplantation Clinical Trial

Official title:
Effects of Physical Exercise on Cognitive Functions in Patients After Allogeneic Stem Cell Transplantation

Clinical Trial Summary

Studies suggest that patients with hematological malignancies undergoing allogeneic hematopoietic stem cell transplantation (HSCT) are at risk for cognitive decline and long-term cognitive dysfunction. To address this issue, a randomized controlled intervention trial on the effect of physical exercise on cognition is conducted. In addition, the impact on psychological and physical health outcomes is evaluated. Results may benefit patients who suffer from disease- or treatment-associated cognitive change.

Clinical Trial Description

Studies suggest that patients with hematological malignancies undergoing allogeneic hematopoietic stem cell transplantation (HSCT) are at risk for cognitive decline and long-term cognitive dysfunction. To address this issue, a randomized controlled intervention trial on the effect of physical exercise on cognition is conducted. In addition, the impact on psychological and physical health outcomes such as depression, fatigue, health-related quality of life and physical fitness is evaluated. A healthy control group matched to the patients on age, gender, and education will be included to both control for practice effects on neuropsychological measures and allow additional comparisons on self-report measures. The healthy control group will undergo neuropsychological testing and questionnaire survey at baseline and 4 months. Demographic data will be collected from all study participants at baseline. Medical data will be collected from patients at all time points. Results may benefit patients who suffer from disease- or treatment-associated cognitive change. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02533947
Study type Interventional
Source Universitätsklinikum Hamburg-Eppendorf
Contact Angela Scherwath, Dr. phil.
Phone +49(40) 7410- 57565
Email a.scherwath@uke.de
Status Recruiting
Phase N/A
Start date June 2014
Completion date August 2019
View Details
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