Effect of Exercise on Cognitive Function and Mental Health in Heroin Addicts

Executive Function Clinical Trial

Official title:

Effect of Exercise on Cognitive Function and Mental Health in Heroin Addicts

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05650983
• Other study ID #: 2022LcLL-30
• Status: Completed
• Phase: N/A
• Start date: April 1, 2021
• Est. completion date: July 1, 2021

Study information

• Verified date: December 2022
• Source: Guangzhou Sport University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The goal of this [type of study: exercise intervention study] is to test in describe participant health conditions. The main questions it aims to answer are:

• [Whether physical exercise improves executive function of male heroin addicts]

• [Whether physical exercise improves negative thinking/affect psychological experience of male heroin addicts] Participants will be randomly selected for medium-intensity strength training (resistance exercise,n=30), 30 will be selected for 1-hour long balloon volleyball sessions (aerobic exercise) at 60-70% volume of oxygen uptake during peak exercise, weekly 5 times for 12 weeks; and 30 will be assigned to the no-exercise control group, Participants will perform Executive function tests and the Symptom Checklist-90 Revised questionnaire at pre and post intervention.

Researchers will compare resistance exercise group,aerobic exercise group and no-exercise control group to see if effects of exercise on executive function and negative thinking/affect psychological experience of male heroin addicts.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 90
• Est. completion date: July 1, 2021
• Est. primary completion date: July 1, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 45 Years

Eligibility

Inclusion Criteria:

• were men who met the Manual of Mental Disorders (DSM)-IV criteria for current heroin dependence

Exclusion Criteria:

• any major mental illness other than heroin addiction

• any exercise taboo

Related Conditions & MeSH terms

• Cerebrovascular Disorders
• Executive Function
• Substance-Related Disorders

Intervention

Behavioral:
• Aerobic exercise; Resistance exercise
To investigate affect/effect of dissimilar modes of exercise, Aerobic exercise versus Resistance exercise, on execution function and psychological symptoms in heroin addicts, 1 hour of characteristic exercise protocols aiming to (a) maximize the strain on the cardiovascular system with Aerobic exercise(60-70% of heart rate recovery) and (b) promote the greatest hypertrophy response with Resistance exercise(65% of 1 repetition maximum & repeated up to 15 time) were used. Both exercise programs were designed to match the male heroin addicts, with medium-intensity Strength-Trained for Resistance exercise and playing balloon volleyball for Aerobic exercise. Two exercise groups performed at 65% of their pre-determine peak oxygen uptake.

Locations

Country	Name	City	State
China	Desk and Computer and Playground	Guangzhou	Guangdongsheng

Sponsors (1)

Lead Sponsor	Collaborator
Guangzhou Sport University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	using the Symptom Checklist-90-R (SCL-90-R) questionnaire to investigate the improvement of physical exercise on psychological symptoms in heroin addicts,	Participants will be assessed the Symptom Checklist-90-R (SCL-90-R) questionnaire at pre and post exercise intervention.	Month 3
Primary	using the executive functioning tests to investigate the improvement of physical exercise on executive function in heroin addicts,	Participants will perform executive function test	Month 3