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Exanthema clinical trials

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NCT ID: NCT06263140 Completed - Clinical trials for Vitamin D Deficiency

Vitamin D Levels in Non-immediate Drug Hypersensitivity Case-control Study

Start date: May 30, 2021
Phase:
Study type: Observational

Serum vitamin D levels in drug-induced non-immediate reactions

NCT ID: NCT06178042 Completed - White Spot Lesion Clinical Trials

Effectiveness of MI Paste Plus and Remin Pro on Remineralization of Post-Orthodontic White Spot Lesions

Start date: February 1, 2020
Phase: N/A
Study type: Interventional

One of the most undesired side effects of fixed orthodontic treatment is white spot lesions (WSLs), that appear on the buccal surface of teeth and cause aesthetic problems. The aim of this prospective study was to quantitively evaluate the remineralization effect of casein phosphopeptide-amorphous calcium fluorophosphate (CPP-ACFP) containing (MI Paste Plus®) and hydroxyapatite, xylitol and fluoride containing (Remin Pro®) agents in remineralizing post orthodontics white spots using Quantitive Light-Induced Fluorescence Method (QLF) and ICDAS II criteria, compared to a control group in whom just a routine home care was instructed. Thirty-nine individuals who had recently completed orthodontic treatment, had at least one WSL on upper anterior teeth and aged between 12-25 years were included. The participants were randomly assigned into three groups of 13 each; (1) MI Paste Plus + routine home care; (2) Remin Pro + routine home care; and (3) routine home care (control). The treatment/ observation period was 12 weeks after bracket debonding. Fluorescence loss (∆F, %), lesion area (LA, mm2), lesion volume (∆Q, % × mm2), maximum fluorescence loss (∆Fmax), ICDAS II criteria of WSLs were measured at beginning (T0) and 4 (T1), 8 (T2), and 12 (T3) weeks later. Statistical significance was set at p<0.05.

NCT ID: NCT06051981 Not yet recruiting - White Spot Lesion Clinical Trials

White Spot Lesions Treatment in Orthodontic

WSL
Start date: October 2023
Phase: Phase 4
Study type: Interventional

The study aims to investigate the effectiveness of a new treatment for demineralized white spot lesions (WSLs) after fixed appliance therapy. The trial will consist of four parallel groups: control, Fluoride Varnish (FV), Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP), and Resin Infiltration (RI) groups. Patients will be recruited from Riyadh Elm University's electronic record system and contacted by phone. They will be given an appointment to visit the dental clinic. A total of 22 patients with WSLs will be selected for the study. Two examiners will perform dental examinations using a dental mirror and a ball-ended probe to code the WSL against the ICDAS system. The level of agreement between the two examiners will be assessed using reliability analysis, with an agreement level of above 80% considered. Buccal WSLs will be defined as those that extend from the center of the buccal to either the mesial or distal surface. WSLs coded 3 or higher will be excluded from further examination and treated accordingly.

NCT ID: NCT05969132 Not yet recruiting - Clinical trials for Altered Passive Eruption of Teeth

Digital Versus Conventional Guided Gingivectomy

Start date: October 1, 2023
Phase: N/A
Study type: Interventional

The goal of this randomized controlled clinical study is to compare Fully digital to conventional guided Gingivectomy procedure in management of excessive gingival display caused by altered passive eruption type 1A. The main question it aims to answer is: Does the fully digital guided gingivectomy approach able to introduce a more precise, accuracy and reliability technique with more patient satisfaction compared to the conventional guided method?

NCT ID: NCT05902611 Recruiting - Dental Caries Clinical Trials

The Relationship Between Body Mass Index, Dental Eruption and Dental Caries Prevalence in School Children

Start date: April 21, 2021
Phase:
Study type: Observational

The aim of the current study will be to explore the relationship between body mass index, dental eruption and dental caries prevalence in school Children.

NCT ID: NCT05871619 Completed - Clinical trials for White Spot Lesion of Tooth

Combined Application of Diode Laser and Different Remineralizing Agents on White Spot Lesions

Whitespot
Start date: May 5, 2022
Phase: N/A
Study type: Interventional

Dental caries is a very common condition, and although it has become less common, it still represents a serious public health risk. Caries symptoms range from the earliest molecular alterations in the tooth's apatite crystals to an apparent white spot lesion (WSL) or eventual cavitation. The white spot lesion looks chalky because minerals are being lost from both the surface and the underside of the enamel. A relatively simple and noninvasive caries preventive regimen in treating white spot lesions with low-level laser irradiation, either alone or with topical fluoride treatment. This treatment results in reduced enamel solubility and dissolution.

NCT ID: NCT05775250 Completed - White Spot Lesion Clinical Trials

Evaluation of Two Varnishes on the Improvement of White Spot Lesions in Children

Start date: March 15, 2023
Phase: N/A
Study type: Interventional

A randomized control trial evaluating the effect of the Giomer varnish versus fluoride varnish on the color improvement of the white spot lesion in permanent anterior teeth of children aged between 8-14 years by using a spectrophotometer at baseline, after 1 month, 3 months and 6 months

NCT ID: NCT05757440 Completed - Clinical trials for White Spot Lesion of Tooth

Effect of Low-viscosity Resin Infiltration on Color Change of Enamel White Spot Lesions

Start date: November 20, 2020
Phase: N/A
Study type: Interventional

this study aimed to assess the effect of the application of the low-viscosity Icon resin infiltrate on the color change of the diagnosed white spot enamel lesions (WSLs) over 3-, 6-, and 12-m follow-up periods. The ICDAS scoring system was used to visually diagnose WSLs in a total of 96 anterior teeth in 49 participants and the teeth were then were evaluated for their color change using a spectrophotometer. According to the manufacturer directions the Icon kit was applied to the WSLs-diagnosed teeth as follows: the WSLs were treated with 15% hydrofluoric acid (Icon-Etch) was applied to the lesions for 120 seconds then it was rinsed for 30 seconds. Next, the etched WSLs were treated with 99% ethanol (Icon-dry) and for 30 seconds. Then the Icon-Resin was applied and light cured for 40 seconds. The change of color was done after 3-, 6- and 12-month . The mean and standard deviation values were statistically analyzed with the repeated measure ANOVA test and the Paired sample t-test.

NCT ID: NCT05738369 Active, not recruiting - White Spot Lesion Clinical Trials

The Effect of Probiotic Lozenges on White Spot Lesion Development in Orthodontic Patients

Start date: February 14, 2022
Phase: N/A
Study type: Interventional

The goal of this randomized clinical trial was to investigate the effect of probiotic lozenges on the development of white spot lesions (WSLs) compared to a positive control, and no treatment.

NCT ID: NCT05604339 Completed - Physiology Clinical Trials

Study of Recovery and Blood Rheology Changes in Ultra-endurance Runners (ERUPTION-3)

ERUPTION-3
Start date: September 20, 2022
Phase:
Study type: Observational

While the acute consequences of an ultratrail are beginning to be well documented, data on the study of recovery in the aftermath of an event are much rarer. In order to overcome these various limitations, the main study of the ERUPTION-3 project is set up on the Grand Raid de La Réunion 2022 races. In the context of exercise responses, the rheological properties of blood can impact the endurance performance. In contrast to short-distance events, the study of blood rheology and red blood cells integrity in long-distance events such as ultra-endurance races is poorly documented in the literature. In the ancillary study, the work that is intended to be carried y out will complement the initial results found by a previous research on 23 runners during the Ultra Trail du Mont Blanc. This ancillary study will also be an opportunity to complete the data from the main study by studying the kinetics of biomarker recovery.