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Exacerbation Copd clinical trials

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NCT ID: NCT05779384 Completed - Clinical trials for Pulmonary Disease, Chronic Obstructive

The COPD Attack Study

COPA
Start date: July 7, 2019
Phase:
Study type: Observational

The goal of this observational study is to evaluate the frequency and predictors of exacerbations in COPD patient population in Uganda. The main questions it aims to answer are:- 1. What is the proportion of frequent exacerbators (≥2/year) and what factors are associated with the frequent exacerbator phenotype? 2. What is the frequency of exacerbations and what factors are correlated with exacerbation frequency? Participants will be asked to offer demographic ,clinical and exposure questions. Questionnaires assessing disease burden, and quality of life will be administered. Clinical measurements, and complete blood count will be collected ta baseline and on sick visits. Spirometry will be measured at baseline and on the last visit. Samples will be collected for storage. Participants will be followed up for one year.

NCT ID: NCT05750810 Completed - COPD Clinical Trials

Exacerbations and Their Outcomes International (EXACOS International)

Start date: April 2012
Phase:
Study type: Observational [Patient Registry]

The aim of this study is to quantify the burden of severe AECOPD in South Korea, by investigating the association between frequency of severe AECOPD and clinical and health-care utilization outcomes.

NCT ID: NCT05380869 Completed - Clinical trials for Community-acquired Pneumonia

POCT PCT in Outpatient LRTI

POCT-PCT
Start date: April 1, 2020
Phase: N/A
Study type: Interventional

Lower respiratory tract infections (LRTI) in patients with chronic lung diseases are a common acute reason to consult respiratory practitioners and often lead to inadequate prescription of antibiotics. The primary objective of the investigators study was to determine the diagnostic accuracy of point-of-care testing (POCT) for procalcitonin (PCT) in identifying pneumonia as a bacterial infection in outpatients with LRTI.

NCT ID: NCT04802096 Completed - Exacerbation Copd Clinical Trials

Effects of Inspiratory Muscle Training in Addition to Pulmonary Rehabilitation in Patients With COPD Exacerbation

Start date: March 15, 2021
Phase: N/A
Study type: Interventional

Inspiratory muscle weakness, limited functional exercise capacity and worse quality of life have been shown in patients with exacerbation of chronic obstructive pulmonary disease (COPD). Recommendations from clinical practice guideline state that promoting pulmonary rehabilitation after exacerbation can improve the conditions above. Inspiratory muscle training (IMT) has been proven to enhance inspiratory muscle strength and endurance in patient with stable COPD. However, there is less research on whether IMT in addition to pulmonary rehabilitation after exacerbation can benefit inspiratory muscle function, functional exercise capacity and quality of life in patients with COPD. The purpose of this study is to examine the effects of IMT in addition to pulmonary rehabilitation on respiratory muscle function, functional exercise capacity and quality of life in patients with exacerbation of chronic obstructive pulmonary disease.

NCT ID: NCT04122547 Completed - Bronchiectasis Clinical Trials

Efficacy of Roflumilast on Exacerbations in Patients With Non-cystic Fibrosis Bronchiectasis

Start date: January 2015
Phase: Phase 3
Study type: Interventional

Roflumilast compare with placebo for decrease infected exacerbation in non-cystic Bronchiectasis

NCT ID: NCT03256604 Completed - Pneumonia Clinical Trials

A Sputum Screening Test to Rule-out Pneumonia at an Early Stage

self-test
Start date: November 2015
Phase: N/A
Study type: Observational

In patients with clinical symptoms of respiratory infection, rapid identification of cases requiring antibiotic therapy is crucial to avoid development of multiple resistant bacteria. Identification of local acute-phase reactants can help assess the host's response to bacterial infection at the injury site. Here, the investigators developed an affordable, stable, feasible, and accurate diagnostic tool based on a locally produced protein with specific binding affinity to polysaccharides. The investigators further evaluated the ability of the novel test strip to rule out pneumonia.

NCT ID: NCT02972775 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

15-year Mortality After Hospitalization for Exacerbation of Chronic Obstructive Pulmonary Disease

MORTCOP
Start date: January 2005
Phase:
Study type: Observational

The investigators examine the 15-year mortality after an admission for an exacerbation of Chronic Obstructive Pulmonary disease (COPD).