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Eutopic Endometrium clinical trials

View clinical trials related to Eutopic Endometrium.

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NCT ID: NCT04010487 Recruiting - Endometrial Cancer Clinical Trials

Multi-omics Study on the Pathogenesis of Malignant Transformation of Adenomyosis

Start date: July 16, 2019
Phase:
Study type: Observational

This study is to explore the driving genes and the molecular mechanism of malignant transformation of adenomyosis. This study acquired the formalin fixed paraffin-embedded (FFPE) tissue of patients pathologically conformed endometrial carcinoma arising in adenomyosis (EC-AIA) treated at Peking Union Medical College Hospital from July 15, 2017 to July 15, 2019. The formalin fixed paraffin-embedded tissues from patients pathologically diagnosed with adenomyosis during this time period were also included as control specimens. The eutopic endometrium, normal adenomyosis tissue, and EC-AIA tissue were harvested from the FFPE tissue from patients with EC-AIA. The normal eutopic endometrium and normal adenomyosis tissue were obtained by laser microdissection. The driving genes and potential molecular mechanism of EC-AIA will be found by the technology of whole exome sequencing and transcriptomics (RNA-sequencing).

NCT ID: NCT03742843 Recruiting - Endometriosis Clinical Trials

A Multi-omics Study of Adenomyosis

Start date: November 10, 2018
Phase:
Study type: Observational

This study aims to analyze the multi-omics results between eutopic endometrium, adenomyosis and endometriosis of patients diagnosed of adenomyosis with and without endometriosis. The multi-omics profiles include whole exome sequencing, analysis of transcriptomics and metabolomics. A comprehensive multi-omics will reveal the pathogenesis of adenomyosis.