Myelofibrosis Clinical Trial
Official title:
Research Tissue Bank
This study that will allow for the preservation and/or storage of a small portion one or more
of the following tissues:
- Peripheral blood
- Bone marrow
- Bone marrow biopsy
- A phlebotomized unit of blood
- Spleen cells
- Toenail clippings
This material will be used for the study of Myeloproliferative Disorders (MPD) by
researchers. The goals of this research study are to understand the causes of MPDs, how to
diagnose them more easily and how to treat them better. MPD is a disease affecting
hematopoietic stem cells. Hematopoietic stem cells are cells that make blood cells. These
stem cells grow in the center portion of the bones called bone marrow. Under some conditions,
these cells are also found in blood. There are several diseases, which are classified as MPD.
These include polycythemia vera (too many red blood cells), essential thrombocythemia (too
many platelets), and idiopathic myelofibrosis (abnormal blood cells and fibers build up in
the bone marrow). These syndromes carry a high risk of developing leukemia. It is important
to continue to learn more about these blood cancers and to learn more about the effectiveness
and potential side effects of various treatments.
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