Interventions Made to Preserve Cognitive Function — IMPCT  

ESRD Clinical Trial

Official title: Hemodialysis-based Interventions to Preserve Cognitive Function

Status Active, not recruiting

Clinical Trial Summary

This is a randomized, controlled trial to slow cognitive decline in adults undergoing hemodialysis (HD). The investigators will test three interventions cognitive training (CT), exercise training (ET), and combined cognitive and exercise training (CT+ET) relative to standard of care (SC).

Clinical Trial Description

This will be a two by two factorial, randomized, controlled trial to slow cognitive decline in adults undergoing hemodialysis (HD). The investigators primary objective is to determine if receiving cognitive training (tablet-based brain games), exercise training (stationary foot pedal), or combined cognitive and exercise training preserves executive function relative to those with standard of care . The secondary objectives are to compare the rates of end stage renal disease (ESRD)-specific clinical outcomes and patient centered outcomes among those receiving CT, or ET, or CT+ET relative to those in SC. The investigators will formally test whether receiving CT or ET will preserve executive function and receiving combined CT+ET will preserve executive function better than CT or ET alone. ;

Related Conditions & MeSH terms

• ESRD

• NCT number: NCT03616535
• Study type: Interventional
• Source: Johns Hopkins University
• Status: Active, not recruiting
• Phase: N/A
• Start date: August 30, 2018
• Completion date: December 8, 2024