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Esophagitis clinical trials

View clinical trials related to Esophagitis.

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NCT ID: NCT05543512 Enrolling by invitation - Clinical trials for Eosinophilic Esophagitis

The Immune Directed Individualized Elimination Therapy (iDIET) Study

iDIET
Start date: October 14, 2022
Phase: N/A
Study type: Interventional

This is a randomized, double blind, sham-controlled, pilot/feasibility trial of individualized dietary elimination treatment.

NCT ID: NCT05488405 Completed - Clinical trials for Eosinophilic Esophagitis

Mesalazine Oral Suspension in Active Eosinophilic Esophagitis

Start date: February 9, 2023
Phase: Phase 2
Study type: Interventional

Pilot study to assess a mesalazine oral suspension in active eosinophilic esophagitis

NCT ID: NCT05485779 Completed - Clinical trials for Eosinophilic Esophagitis (EoE)

SAD, MAD and Food Effect Evaluation of Safety, Tolerability, and PK of AQ280 in Healthy Subjects

Start date: July 20, 2022
Phase: Phase 1
Study type: Interventional

The principal aim of this study is to obtain safety and tolerability data when AQ280 is administered orally as single and multiple doses to healthy subjects. This information, together with the pharmacokinetic (PK) data, will help establish the doses and dosing regimen suitable for future studies in patients.

NCT ID: NCT05485155 Recruiting - Clinical trials for Eosinophilic Esophagitis

Zemaira Eosinophilic Esophagitis Pilot Study

ZEEPS
Start date: September 1, 2024
Phase: Phase 2
Study type: Interventional

This is a prospective, open-label drug study that will examine the effects of Zemaira (alpha-1 trypsin inhibitor) in patients with Eosinophilic Esophagitis.

NCT ID: NCT05482256 Active, not recruiting - Clinical trials for Eosinophilic Esophagitis

A Study of Detergents in the Pathogenesis of Eosinophilic Esophagitis

Start date: September 12, 2022
Phase: N/A
Study type: Interventional

The purpose of this research is to determine if detergents in everyday products such as toothpaste make the lining of the esophagus leaky and cause allergic inflammation.

NCT ID: NCT05444543 Completed - Clinical trials for Eosinophilic Esophagitis

Cycling of Topical Steroids for Treatment of EoE (Eosinopilic Esophagitis)

Start date: November 17, 2021
Phase: Phase 4
Study type: Interventional

The purpose of our research study is to assess whether patients with EoE who have achieved control of their disease on topical Fluticasone or Budesonide are able to cycle or take breaks from their treatment with continued remission of their EoE. There will be 30 participants enrolled in this study. There will be 15 patients who will stay on steroid therapy every day and 15 patients who will cycle their steroid therapy on and off to help us compare the two groups. The cycling group will cycle their steroid therapy in a three-months on three-months off fashion.

NCT ID: NCT05443984 Recruiting - Erosive Esophagitis Clinical Trials

JP-1366 20mg Versus Esomeprazole 40mg in Patients With Erosive Esophagitis

Start date: January 17, 2022
Phase: Phase 3
Study type: Interventional

To evaluate the efficacy and safety of JP-1366 20 mg compared to esomeprazole 40 mg in patients with erosive esophagitis

NCT ID: NCT05418920 Not yet recruiting - Esophagitis, Reflux Clinical Trials

Clinical Trial of Reconstruction After Proximal Gastrectomy

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

1) To explore a simple, safe, post-proximal gastrectomy reconstruction method with good absorption and digestive function in order to improve patients' postoperative quality of life; 2) To fill the gap in the comparison of clinical efficacy between left-open single-flap technique and double-flap technique in this specialized field in China; 3) To utilize the experience and foundation of gastrointestinal surgery in the treatment of gastric cancer and integrate the advantageous resources in China; 4) To establish a large-sample, multicenter randomized clinical study in order to promote the establishment and improvement of relevant norms of gastrointestinal reconstruction

NCT ID: NCT05369234 Recruiting - Esophageal Cancer Clinical Trials

Effects of Oral Aloe Vera Juice on Chemotherapy and Radiation-induced Oral Mucositis and Esophagitis

Start date: January 20, 2022
Phase: Phase 3
Study type: Interventional

As mentioned above, several prior studies have shown the positive effects of oral use of aloe vera juice in managing chemotherapy and radiation-induced oral mucositis and esophagitis. This study aims to add to the existing body of research around aloe vera juice and its effects on oral mucositis and esophagitis. The intention is to determine whether aloe vera juice should be considered as part of standard treatment.

NCT ID: NCT05342168 Recruiting - Clinical trials for Eosinophilic Esophagitis

Comparison of Histology From a Mesh Sponge and Traditional Esophageal Biopsies in Children and Adolescents With EoE

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

The aim of the present study is determining the accuracy, safety and tolerance of the CytospongeTM (expandable sponge within a gelatin capsule attached to a string) relative to traditional upper endoscopy and esophageal biopsies in older children and adolescents with a diagnosis of Eosinophilic Esophagitis (EoE) to follow up on treatment changes. The findings from this study could help determine whether the CytospongeTM is a more cost-effective alternative to traditional upper endoscopy for histologic follow-up in children and adolescents with EoE.