Reduction in Symptomatic Esophageal Stricture Formation

Esophageal Stenosis Clinical Trial

Official title:
Reduction in Symptomatic Esophageal Stricture Formation Post-two Stage Complete Barrett's Excision for High Grade Dysplasia or Early Adenocarcinoma With Short-term Steroid Therapy: A Randomized, Double-blinded, Placebo-controlled, Multicenter Trial.

Status Completed

Clinical Trial Summary

Complete endoscopic resection of early neoplastic BE is a curative procedure. However, a significant proportion of patients develop symptomatic esophageal strictures following CBE, and this limits the technique, particularly for circumferential and longer segment disease. Oral steroid therapy may reduce stricture formation; thereby allowing CBE to be performed with minimal associated morbidity.

Clinical Trial Description

The main objective of the proposed randomized trial is to compare the rate of symptomatic oesophageal strictures in patients receiving placebo versus oral prednisone. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02039115
Study type	Interventional
Source	Florida Hospital
Contact
Status	Completed
Phase	Phase 4
Start date	March 2014
Completion date	February 2015

View Details

See also
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