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A Trial of CMNa Combined With Preoperatie Concurrent Chemoradiotherapy for Locally Advanced ESCC

Esophageal Neoplasms Clinical Trial

Official title:
A Perspective Trial of Sodium Glycididazole Combined With Preoperatie Concurrent Chemoradiotherapy for Locally Advanced Squamous Cell Esophageal Carcinoma

Clinical Trial Summary

This is a perspective, multicenter,single arm, open label study to evaluate the efficacy and safety of treatment with CMNa combined with preoperatie concurrent chemoradiotherapy in patients with locally advanced squamous cell esophageal carcinoma . Analyses of primary objective (pathologic Complete Response) will be done as defined in the protocol.

Clinical Trial Description

The primary end ponit of this study is pathological complete response.And the primary hypothesis is the CMNa will improve patholofical response rate and thus improve OS、DFS. Assuming bilateral a=0.05, statistical power of 80%.The total sample size is 40 cases. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02721550
Study type Interventional
Source Shandong Cancer Hospital and Institute
Contact
Status Terminated
Phase Phase 4
Start date August 1, 2016
Completion date June 30, 2018
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