Barrett Esophagus Clinical Trial
Official title:
Endoscopic Submucosal Dissection for the Treatment of Early Barrett's Neoplasia
This study assesses the quality of the resection of early neoplasia arinsing in Barrett's esophagus using endoscopic submucosal dissection. It is a multicenter prospective registry among 7 centers including all consecutive patients with early Barrett's neoplasia of 15 mm or more in size treated by endoscopic submucosal dissection.
Endoscopic submucosal dissection ( ESD) demonstrated great efficacy in the treatment of
squamous cell carcinoma of the esophagus. Results for the treatment of esophageal
adenocarcinoma arising in Barrett's esophagus are conflicting.
In this multicenter prospective registry among 7 French centers, all consecutive patients
with early Barrett's neoplasia of 15 mm or more in size treated by endoscopic submucosal
dissection will be included in the registry. The primary objective is to assess the quality
of the resection by ESD of early Barrett's neoplasia (T1A or T1B sm1 or high grade
dysplasia). Secondary endpoints are to assess the combined efficacy of a treatment
associating ESD and radiofrequency ablation of the remaining Barrett esophagus, and to assess
the durability of the results after 3 years.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT03554356 -
Nitrous Oxide For Endoscopic Ablation of Refractory Barrett's Esophagus (NO FEAR-BE)
|
N/A | |
Completed |
NCT03015389 -
Wide Area Transepithelial Sample Esophageal Biopsy Combined With Computer Assisted 3-Dimensional Tissue Analysis (WATS3D) For the Detection of High Grade Esophageal Dysplasia and Adenocarcinoma
|
||
Completed |
NCT03434834 -
OCT Pilot in Esophagus
|
N/A | |
Terminated |
NCT04642690 -
Nitrates and IL-8 in Barrett's Esophagus
|
||
Completed |
NCT03468634 -
Raman Probe for In-vivo Diagnostics (During Oesophageal) Endoscopy
|
N/A | |
Recruiting |
NCT02310230 -
An Evaluation of the Utility of the ExSpiron Respiratory Variation Monitor During Upper GI Endoscopy
|
N/A | |
Completed |
NCT00217087 -
Endoscopic Therapy of Early Cancer in Barretts Esophagus
|
Phase 2 | |
Completed |
NCT02284802 -
Early Detection of Tumors of the Digestive Tract by Confocal Endomicroscopy
|
N/A | |
Recruiting |
NCT05530343 -
Seattle Biopsy Protocol Versus Wide-Area Transepithelial Sampling in Patients With Barrett's Esophagus Undergoing Surveillance
|
N/A | |
Active, not recruiting |
NCT04151524 -
Classification of Adenocarcinoma of the Esophagogastric Junction
|
||
Completed |
NCT00955019 -
Novel Method of Surveillance in Barrett's Esophagus
|
Phase 2 | |
Terminated |
NCT00386594 -
Pilot Study of Oral 852A for Elimination of High-Grade Dysplasia in Barrett's Esophagus
|
N/A | |
Completed |
NCT00576498 -
Novel Imaging Techniques in Barrett's Esophagus
|
N/A | |
Completed |
NCT02688114 -
Healing of the Esophageal Mucosa After RFA of Barrett's Esophagus
|
N/A | |
Recruiting |
NCT06071845 -
Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal Samples
|
N/A | |
Completed |
NCT02560623 -
A Minimally-Invasive Sponge on a String Device for Screening for Barrett's Esophagus
|
N/A | |
Recruiting |
NCT05056051 -
Wide-Area Transepithelial Sampling in Endoscopic Eradication Therapy for Barrett's Esophagus
|
N/A | |
Recruiting |
NCT04001478 -
Non-invasive Testing for Early oEesophageal Cancer and Dysplasia
|
||
Completed |
NCT03859557 -
The Evaluation of Patients With Esophageal and Foregut Disorders With WATS (Wide Area Transepithelial Sample With 3-Dimensional Computer-Assisted Analysis) vs. 4-Quadrant Forceps Biopsy
|
||
Completed |
NCT04587310 -
Does Laparoscopic Sleeve Gastrectomy Lead to Barrett's Esophagus, 5-year Esophagogastroduodenoscopy Findings: A Retrospective Cohort Study
|