Esophageal Cancer Clinical Trial
Official title:
18F-AraG PET/CT as a Non-Invasive Imaging Biomarker for Chemoradiation Treatment Response in Esophageal Cancer
To learn if 18F-FAraG PET scans can find tumors in participants with esophageal cancer and predict a participant's response to treatment.
Primary Objectives - Evaluate the ability of 18F-FAraG PET imaging to detect tumors in participants with esophageal cancer; - Evaluate 18F-FAraG PET as a predictor of pathologic complete response Secondary Objectives - Evaluate the correlation of 18F-FAraG PET with clinical characteristics - Evaluate the correlation of 18F-FAraG PET with scRNA-seq data - Evaluate tissue and blood biomarkers as predictors of treatment response and disease recurrence - Evaluate functional imaging with 18F-FAraG PET and tissue and blood biomarkers as predictors of overall survival and disease-free survival - Compare 18F-FAraG PET SUV update to the change in standard 18FDG-PET SUV parameters before and after chemoradiation. ;
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