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ChemoRadiation And Tislelizumab for Esophageal/EGJ Cancer — CRATER  

Esophageal Cancer Clinical Trial

Official title:
ChemoRadiation And Tislelizumab for Esophageal/EGJ Cancer

Clinical Trial Summary

This study aims to determine the effects of chemoradiation and Tislelizumab on Esophageal/EGJ Cancer before and after surgery.

Clinical Trial Description

Esophageal cancer patients in this trial will receive chemoradiation therapy with tislelizumab, which is an anti-PD-1 antibody, before surgery. Patient will be evaluated for complete pathological response or major pathological response rate following chemoradiation. Patient will continue on to get tislelizumab after surgery to complete total of a year of treatment. They will be evaluated for PFS and OS. Throughout the study, drug tolerability and toxicities will be monitored. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05245760
Study type Interventional
Source University of Kentucky
Contact
Status Withdrawn
Phase Phase 2
Start date April 2022
Completion date December 2033
View Details
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