Clinical Trials Logo
  1. Home
  2. Esophageal Atresia
  3. NCT05527873
  4. Details
NCT05527873 Clinical Trial

Respiratory Complications of Operated Esophageal Atresia in Children

Esophageal Atresia Clinical Trial

— ATRESIA  

Official title:
Respiratory Complications of Operated Esophageal Atresia in Children

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05527873
Other study ID # 8562
Secondary ID
Status Completed
Phase
First received
Last updated
Start date March 16, 2022
Est. completion date December 16, 2022

Study information
Verified date November 2023
Source University Hospital, Strasbourg, France
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The respiratory complications of esophageal atresia have already been identified. They are mainly related to tracheomalacia linked to the esophageal malformation, and are aggravated by frequently associated gastroesophageal reflux. In this context, symptoms of asthma (or bronchial hyperreactivity) occur more frequently than in the general population and persist into adulthood. Their pathogenesis is still poorly understood and is the subject of much discussion. The therapeutic management of these respiratory complications, poorly codified, remains very heterogeneous from one center to another. In France, the summary of knowledge is updated by the Reference Center for chronic and malformative diseases of the esophagus.

Recruitment information / eligibility
Status Completed
Enrollment 67
Est. completion date December 16, 2022
Est. primary completion date October 16, 2022
Accepts healthy volunteers
Gender All
Age group 1 Year to 12 Years
Eligibility Inclusion criteria: - Child aged 1 to 12 years old - Child operated on for esophageal atresia between 01/01/2010 and 31/12/2020 and followed up at the University Hospitals of Strasbourg - Child who has not expressed, after being informed, his opposition to the reuse of his data for the purposes of this research - Parental authority having not expressed, after being informed, their opposition to the reuse of their child's data for the purposes of this research. Exclusion criteria: Subject and/or parental authority having expressed their opposition to participating in the study

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
France Centre de Ressources et de Compétences de la Mucoviscidose (CRCM) - CHU de Strasbourg - France Strasbourg

Sponsors (1)
Lead Sponsor Collaborator
University Hospital, Strasbourg, France

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary Retrospective study of respiratory complications of esophageal atresia in children Files analysed retrospectively from January 01, 2010 to December 31, 2020 will be examined
See also
  Status Clinical Trial Phase
Recruiting NCT04072419 - Application of Enhanced Recovery After Surgery for Congenital Esophageal Atresia During Perioperative Period
Withdrawn NCT03127345 - Omega 3 Fatty Acid Treatment for Pediatric Musculoskeletal Health Phase 2
Completed NCT00226044 - Rectal and Oral Omeprazole Treatment of Reflux Disease in Infants. Phase 3
Completed NCT03615495 - Flourish™ Pediatric Esophageal Atresia
Recruiting NCT05995171 - Long Term Outcome of Easophageal Atresia : Transmics Profiles in Adolescence
Completed NCT04901546 - Esophageal Atresia: a Natural Experiment of the Effects of Oral Inoculation on the Gut Microbiome N/A
Recruiting NCT03730454 - Transanastomotic Tube for Proximal Esophageal Atresia With Distal Tracheoesophageal Fistula Repair N/A
Recruiting NCT03455881 - Phenotypic and Genetic Assessment of Tracheal and Esophageal Birth Defects in Patients
Completed NCT04932746 - The Effect of Dexmedetomidine on Oxygen During One Lung Ventilation in Pediatric Surgery. N/A
Not yet recruiting NCT04259528 - Endoscopic Ultrasound Findings in Esophageal Atresia Following Surgical Repair N/A
Recruiting NCT06073158 - Molecular Signatures of Esophageal Atresia N/A
Not yet recruiting NCT03999008 - Oral Viscous Budesonide in Anastomotic Stricture After Esophageal Atresia Repair (OVB in EA) N/A
Completed NCT03415893 - High-resolution Esophageal Manometry N/A
Not yet recruiting NCT03023865 - Individualized Management for Long Gap Esophageal Atresia N/A
Recruiting NCT02883725 - National Register of Oesophageal Atresia
Not yet recruiting NCT04136795 - Evaluation of the Respiratory Impact After Conventional or Minimally Invasive Esophageal Atresia Surgery
Recruiting NCT03619408 - Management of Esophagitis Following Repair of Esophageal Atresia
Completed NCT05129930 - Fluid Overload and Pulmonary Function
Completed NCT02033772 - Prospective Data Collection of Patients < 6 Months of Age Undergoing Thoracoscopic Surgery N/A
Recruiting NCT03767673 - Cardiorespiratory Performance and Pulmonary Microbiome in Patients After Repair of Esophageal Atresia N/A