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Esophageal and Gastric Varices clinical trials

View clinical trials related to Esophageal and Gastric Varices.

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NCT ID: NCT02853526 Recruiting - Liver Cirrhosis Clinical Trials

TIPS for Variceal Rebleeding in Cirrhotic Patients With Occlusive Portal Vein Thrombosis and CTPV

Start date: July 2015
Phase: Phase 3
Study type: Interventional

To date, there is no treatment strategies for these patients according to American Association of the Study of Liver Disease (AASLD) practice guidelines and Baveno V consensus. Thus, we aim to compare the safety and efficacy of TIPS and conservative treatment (non-selective beta blockers, endoscopic therapy and/or anticoagulation) in patients with PVT and CPTV.

NCT ID: NCT02767206 Enrolling by invitation - Liver Cirrhosis Clinical Trials

Evaluation of Gastroesophageal Varices by Transnasal Endoscopy.

Start date: March 2016
Phase: N/A
Study type: Observational

The study aims to evaluate the feasibility of transnasal endoscopy in patients with portal hypertension, cirrhotic and non-cirrhotic. The incidence of the procedure's adverse effects, the patient's tolerance and his/her opinion about the exam are analyzed. In addition, the interobserver matched for the discoveries found in the study is carried out.

NCT ID: NCT02740166 Recruiting - Esophageal Varices Clinical Trials

Preventing Recurrent Bleeding After Eradication of Esophageal Varices

Start date: June 2013
Phase: Phase 4
Study type: Interventional

Esophageal variceal bleeding is a severe complication of portal hypertension. Banding ligation plus non-selective beta-blockers is the current recommendation for prevention of recurrent bleeding. However, the optimal duration of use of non-selective beta-blockers is not well defined. This study aims at comparing the rebleeding rate and adverse effects in patients using or without using propranolol after eradication of esophageal varices.

NCT ID: NCT02719119 Recruiting - Clinical trials for Esophageal and Gastric Varices

Trial of Monthly Versus Bi-weekly Endoscopic Variceal Ligation for the Prevention of Esophageal Variceal Rebleeding

Start date: March 2016
Phase: N/A
Study type: Interventional

Many physicians suggest repeating EVL every 1-2 weeks until esophageal varices are obliterated to prevent variceal rebleeding, however, the evidences supporting the efficacy of EVL intervals of 1-2 weeks are insufficient.This randomized controlled study was conducted in order to compare the long-term results of EVL when performed at two different results from monthly and bi-weekly treatments.

NCT ID: NCT02695732 Recruiting - Liver Cirrhosis Clinical Trials

The Effect of Carvedilol VS Endoscopic Therapy in Primary Prophylaxis of High-risk Esophageal Gastric Variceal Bleeding

Start date: December 2015
Phase: Phase 4
Study type: Interventional

To compare the efficacy and safety of Carvedilol and endoscopic therapy in Primary Prophylaxis of High-risk Esophageal Gastric Variceal Bleeding.

NCT ID: NCT02693951 Recruiting - Cirrhosis Clinical Trials

Efficiency and Safety of Prophylactic Use of Antibiotics in Endoscopic Injection of Tissue Adhesive in Gastric Varices

Start date: February 2016
Phase: N/A
Study type: Interventional

The purpose of the study is to assess the efficiency and safety of prophylactic use of antibiotics in endoscopic injection of tissue adhesive in gastric varices.

NCT ID: NCT02646202 Recruiting - Clinical trials for Gastroesophageal Varices

Scleroligation for Eradication of Gastroesophageal Varices.

Start date: January 2015
Phase: Phase 3
Study type: Interventional

Gastric varices occur in 5-33% of patients with portal hypertension. Concomitant gastro esophageal varices are the most common type. Both endoscopic sclerotherapy and band ligation are very effective in controlling acute esophageal varices bleeding and preventing rebleeding.

NCT ID: NCT02638415 Recruiting - Cirrhosis Clinical Trials

The Effect of Hepatic Vein Pressure Gradient(HVPG)-Guided Therapy in Cirrhotic Patients With Esophagogastric Varices

Start date: December 2015
Phase: Phase 4
Study type: Interventional

The purpose of the study is to compare the effect of HVPG-guided individualized therapy and non-HVPG guided traditional therapy in cirrhotic patients for secondary prophylaxis.

NCT ID: NCT02593799 Completed - Liver Cirrhosis Clinical Trials

Non-invasive Prediction of Esophageal Varices in Liver Cirrhosis: A Multicenter Observational Study

Start date: May 1, 2015
Phase:
Study type: Observational

Esophageal variceal bleeding is one of the most lethal complications of liver cirrhosis. In the early stage of liver cirrhosis, the prediction of esophageal varices is very important for guiding the clinical decision making of primary prophylaxis of variceal bleeding.

NCT ID: NCT02583698 Completed - Clinical trials for Acute on Chronic Liver Failure

Efficacy of Nonselective Beta Blocker vs Placebo in Patients With Acute-on-chronic Liver Failure With Small/ no Esophageal Varices

Start date: October 1, 2015
Phase: N/A
Study type: Interventional

Acute on chronic liver failure patients with HVPG (Hepatic Venous Pressure Gradient) ≥ 12 mmHg + No/small esophageal varices who present to the Department of Hepatology at Institute of Liver and Billiary Sciences, who meet the inclusion criteria and who provide informed consent.