Clinical Trials Logo

Erythropoiesis Abnormal clinical trials

View clinical trials related to Erythropoiesis Abnormal.

Filter by:
  • Completed  
  • Page 1

NCT ID: NCT05833477 Completed - Erythrocytosis Clinical Trials

Tracing Changed Production of Red Blood Cells

Start date: October 28, 2022
Phase: N/A
Study type: Interventional

In competitive sport, it is illegal to manipulate erythropoiesis. Manipulated erythropoiesis can indirectly be identified by atypical fluctuations in key haematological variables. However, this method also has limitations and as it is known that some athletes still manipulate erythropoiesis it is necessary to develop new and more sensitive detection methods. The primary purpose of the study is to examine the importance of altered erythropoiesis for surface and intracellular erythrocyte proteins, the number of immature reticulocytes, and for the haematological characteristics of the erythrocyte, such as volume, haemoglobin concentration and concentration of glycosylated haemoglobin, to assess whether these can be used to identify changed erythropoiesis. Furthermore, the aim is to examine whether these parameters are affected by freezer storage of erythrocytes.

NCT ID: NCT04744181 Completed - Anemia Clinical Trials

Patient Blood Management In CARdiac sUrgical patientS

ICARUS
Start date: January 18, 2021
Phase:
Study type: Observational

Nowadays up to 40% of patients undergoing cardiac surgery receives at least 1 unit of red blood cell transfusion during surgery or during the first week after surgery. Moreover up to 40% of these patients shows an absolute or relative iron deficiency, with or without anaemia. The objective of this study is to assess whether to implement an adequate correction of iron according to current "patients blood management" recommendations might reduce RBC transfusion requirements in patients undergoing heart surgery. Data obtained in patients included in the study will be compared to those of a case-control population selected from patients consecutively treated at the same department in the previous 2 years.